dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2018-11-26T17:04:27Z | |
dc.date.available | 2018-11-26T17:04:27Z | |
dc.date.created | 2018-11-26T17:04:27Z | |
dc.date.issued | 2016-07-01 | |
dc.identifier | Revista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 49, n. 4, p. 491-493, 2016. | |
dc.identifier | 0037-8682 | |
dc.identifier | http://hdl.handle.net/11449/161869 | |
dc.identifier | 10.1590/0037-8682-0105-2016 | |
dc.identifier | S0037-86822016000400491 | |
dc.identifier | WOS:000382457200015 | |
dc.identifier | S0037-86822016000400491.pdf | |
dc.identifier | 3587895085226224 | |
dc.identifier | 5020559826568182 | |
dc.identifier | 0000-0001-9200-5391 | |
dc.identifier | 0000-0003-1948-5071 | |
dc.description.abstract | Introduction: In this study, we evaluated hepatitis C virus (HCV) and human immunodeficiency virus (HIV) - platelet interactions in vitro as well as human platelets antigen (HPA) polymorphisms. Methods: Platelets were obtained from 100 healthy HPA-genotyped volunteer donors and incubated with HIV or HCV. The viral load after in vitro exposure was detected. Results: The viral load in the platelets after exposure to the virus was higher in the HIV exposure than in the HCV exposure. Conclusions: HIV-platelet ligation could be more efficient than HCV-platelet interaction. Further, the HPA-1b allele seems to influence the interaction of platelets with HCV. | |
dc.language | eng | |
dc.publisher | Soc Brasileira Medicina Tropical | |
dc.relation | Revista Da Sociedade Brasileira De Medicina Tropical | |
dc.relation | 0,658 | |
dc.rights | Acesso aberto | |
dc.source | Web of Science | |
dc.subject | Hepatitis C virus | |
dc.subject | Human platelets antigen polymorphisms | |
dc.subject | Human immunodeficiency virus | |
dc.title | Human platelets antigens influence the viral load of platelets after the interaction of the platelets with HCV and HIV in vitro | |
dc.type | Artículos de revistas | |