Synthesis of Analogues of Thyroid Hormones: Nuclear Receptor Modulators

dc.contributorUniversidade Federal do ABC (UFABC)
dc.contributorUniversidade de São Paulo (USP)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-11-26T16:05:25Z
dc.date.available2018-11-26T16:05:25Z
dc.date.created2018-11-26T16:05:25Z
dc.date.issued2015-07-01
dc.identifierOrbital-the Electronic Journal Of Chemistry. Campo Grande: Univ Federal Mato Grosso Sul, Dept Quimica, v. 7, n. 3, p. 282-291, 2015.
dc.identifier1984-6428
dc.identifierhttp://hdl.handle.net/11449/160636
dc.identifier10.17807/orbital.v7i3.739
dc.identifierWOS:000219762300011
dc.identifierWOS000219762300011.pdf
dc.identifier7989837727910759
dc.identifier0000-0002-5240-4870
dc.description.abstractThyroid hormones are essential for the development and differentiation of all cells of the human body. This work reports the synthesis of some synthetic structural analogues of thyroid hormones, which may be modulators of the thyroid hormone receptor. The known compounds GC-1 (Sobetirome) and CG-24 were successfully prepared and two novel analogous molecules were also synthesized by a new and efficient synthetic methodology.
dc.languageeng
dc.publisherUniv Federal Mato Grosso Sul, Dept Quimica
dc.relationOrbital-the Electronic Journal Of Chemistry
dc.rightsAcesso aberto
dc.sourceWeb of Science
dc.subjectthyroid hormones
dc.subjectnuclear receptor
dc.subjectligands
dc.subjectsynthesis
dc.titleSynthesis of Analogues of Thyroid Hormones: Nuclear Receptor Modulators
dc.typeArtículos de revistas


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