Estudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-03-02T12:57:52Z
dc.date.available2016-03-02T12:57:52Z
dc.date.created2016-03-02T12:57:52Z
dc.date.issued2011
dc.identifierOrbital: the Electronic Journal of Chemistry, v. 3, n. 1, p. 1-14, 2011.
dc.identifier1984-6428
dc.identifierhttp://hdl.handle.net/11449/134664
dc.identifierISSN1984-6428-2011-03-01-01-14.pdf
dc.identifier9231608553951292
dc.identifier9154336767369306
dc.description.abstractThe aim of this work was to investigate the use of NbCl5 as Lewis acid in cycloadittion reactions [Reaction Aza-Diels-Alder (Povarov)] between Schiff bases and enol ethers. Comparison of reaction yields, obtained products as well as reaction time with NbCl5 were also a key point on this work. In the aza-Diels-Alder reactions between Schiff bases and enol ethers (dihydropyran or dihydrofuran), the NbCl5 was an excellent catalyst for the synthesis of pyrano- and furanoquinoline derivatives. These derivatives are an important class of natural products that exhibit wide range of biological activity. The reactions were carried out at low concentration of niobium and in relatively short times, resulting in yields varying from 78 to 95%.
dc.languagepor
dc.relationOrbital: the Electronic Journal of Chemistry
dc.rightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectNiobium pentachloride
dc.subjectPovarov reactions
dc.subjectTetrahydroquinoline derivatives
dc.subjectAza-Diels-Alder reactions
dc.titleEstudos sobre o uso de NbCl5 como ácido de Lewis em reações de Povarov
dc.typeArtículos de revistas


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