Validation of cefazolin sodium by UV-spectrophotometric method

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2016-01-28T16:56:42Z
dc.date.available2016-01-28T16:56:42Z
dc.date.created2016-01-28T16:56:42Z
dc.date.issued2013
dc.identifierPhysical Chemistry, v. 3, n. 1, p. 11-20, 2013.
dc.identifier2167-7042
dc.identifierhttp://hdl.handle.net/11449/133812
dc.identifier10.5923/j.pc.20130301.03
dc.identifier4238972287355427
dc.identifier9881720291571774
dc.description.abstractA simple, fast and reproducible UV Spectrophotometric method was developed and validated for quantification of cefazolin sodium in pharmaceutical form powder for injectable solution, the method proved effective, easy applicability, low cost, besides it does not generate toxic wastes to the operator and the environment, corroborating with the routine analysis of quality control to ensure the therapeutic efficacy of the drug already marketed. The method presented being capable to detect and quantify the drug obtaining satisfactory results regarding specificity, precision, accuracy and robustness, linear range of 8 to 28 µg/mL, showing correlation coefficient of 0.9999 when analyzed in the wavelenght λ=270 nm spectrophotometer.
dc.languageeng
dc.publisherScientific and Academic Publishing
dc.relationPhysical Chemistry
dc.rightsAcesso restrito
dc.sourceCurrículo Lattes
dc.subjectCefazolin sodium
dc.subjectCephalosporin
dc.subjectAnalytical method
dc.subjectQuantitative analysis
dc.subjectQuality control
dc.titleValidation of cefazolin sodium by UV-spectrophotometric method
dc.typeArtículos de revistas


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