Synthesis and antitubercular evaluation of new 1,2,3-triazole derivatives of carbohydrates

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade Federal de Juiz de Fora (UFJF)
dc.date.accessioned2016-01-28T16:56:19Z
dc.date.available2016-01-28T16:56:19Z
dc.date.created2016-01-28T16:56:19Z
dc.date.issued2012
dc.identifierMediterranean Journal of Chemistry, v. 1, n. 6, p. 281-288, 2012.
dc.identifier2028-3997
dc.identifierhttp://hdl.handle.net/11449/133718
dc.identifier10.13171/mjc.1.6.2012.02.05.15
dc.identifierISSN2028-3997-2012-01-06-281-288.pdf
dc.identifier9818597076971227
dc.identifier2114570774349859
dc.description.abstractWe reported in this work the preparation of novel 1,4-disubstituted-1,2,3-triazoles derivatives from Dglucose and D-fructose and their in vitro antibacterial activity against Mycobacterium tuberculosis were evaluated. The chemical synthesis was performed based on the 1,3-dipolar cycloaddition reaction, and antimicrobial activity was determined based on Resazurin Microtiter Assay against Mycobacterium. None of the triazole glycoconjugates tested showed activity against these microorganisms.
dc.languageeng
dc.relationMediterranean Journal of Chemistry
dc.rightsAcesso aberto
dc.sourceCurrículo Lattes
dc.subjectCarbohydrate
dc.subjectGlycoconjugates
dc.subject1,2,3-triazole
dc.subjectAntitubercular activity
dc.titleSynthesis and antitubercular evaluation of new 1,2,3-triazole derivatives of carbohydrates
dc.typeArtículos de revistas


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