Artículos de revistas
Supported core-shell nanobiosensors for quantitative fluorescence imaging of extracellular pH
Fecha
2014Registro en:
Chemical Communications, v. 50, n. 89, p. 13746-13749, 2014.
1359-7345
10.1039/C4CC06075J
ISSN1359-7345-2014-50-89-13746-13749.pdf
2998503841917815
Autor
Université Laval
Universidade Estadual Paulista (Unesp)
Institución
Resumen
Covalent “click” cycloaddition was used to functionalize silica substrates with pH-sensitive nanoparticles, thus producing uniform and highly luminescent analytical devices usable in both commercial fluorimeters and fluorescence microscopes. Quantitative and spatially-resolved extracellular pH measurements were successfully achieved on live cardiac fibroblasts with these novel ion-sensitive surfaces.