Does Calretinin Immunohistochemistry Reduce Inconclusive Diagnosis in Rectal Biopsies for Hirschsprung Disease?

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-12-03T13:10:37Z
dc.date.available2014-12-03T13:10:37Z
dc.date.created2014-12-03T13:10:37Z
dc.date.issued2014-05-01
dc.identifierJournal Of Pediatric Gastroenterology And Nutrition. Philadelphia: Lippincott Williams & Wilkins, v. 58, n. 5, p. 603-607, 2014.
dc.identifier0277-2116
dc.identifierhttp://hdl.handle.net/11449/112316
dc.identifier10.1097/MPG.0000000000000263
dc.identifierWOS:000335653600021
dc.description.abstractMany difficulties occur during the evaluation of rectal biopsies for the diagnosis of Hirschsprung disease. We investigated whether the introduction of calretinin (CR) immunohistochemistry in a diagnostic panel could decrease the rate of inconclusive results. Data from 82 patients undergoing rectal biopsies before and after CR introduction were analyzed. Inconclusive results were obtained in 17 of 45 rectal biopsies (37.8%) in the series of cases before CR introduction and in 5 of 42 rectal biopsies (11.9%) in the series of cases after CR (P < 0.006). The inclusion of CR in the histopathologic panel may improve the diagnostic accuracy of Hirschsprung disease.
dc.languageeng
dc.publisherLippincott Williams & Wilkins
dc.relationJournal of Pediatric Gastroenterology and Nutrition
dc.relation2.752
dc.relation1,376
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectHirschsprung disease
dc.subjectrectal suction biopsies
dc.subjectcalretinin immunohistochemistry
dc.titleDoes Calretinin Immunohistochemistry Reduce Inconclusive Diagnosis in Rectal Biopsies for Hirschsprung Disease?
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución