dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-12-03T13:10:36Z
dc.date.available2014-12-03T13:10:36Z
dc.date.created2014-12-03T13:10:36Z
dc.date.issued2014-07-12
dc.identifierPediatric Rheumatology. London: Biomed Central Ltd, v. 12, 5 p., 2014.
dc.identifier1546-0096
dc.identifierhttp://hdl.handle.net/11449/112315
dc.identifier10.1186/1546-0096-12-27
dc.identifierWOS:000339285500001
dc.identifierWOS000339285500001.pdf
dc.identifier7098310008371632
dc.identifier0000-0002-7631-7093
dc.description.abstractBackground: Muscle atrophy and asymmetric extremity growth is a common feature of linear scleroderma (LS). Extra-cutaneous features are also common and primary neurologic involvement, with sympathetic dysfunction, may have a pathogenic role in subcutaneous and muscle atrophy. The aim was investigate nerve conduction and muscle involvement by electromyography in pediatric patients with LS.Methods: We conducted a retrospective review of LS pediatric patients who had regular follow up at a single pediatric center from 1997-2013. We selected participants if they had consistently good follow up and enrolled consecutive patients in the study. We examined LS photos as well as clinical, serological and imaging findings. Electromyograms (EMG) were performed with bilateral symmetric technique, using surface and needle electrodes, comparing the affected side with the contralateral side. Abnormal muscle activity was categorized as a myopathic or neurogenic pattern.Results: Nine LS subjects were selected for EMG, 2 with Parry-Romberg/Hemifacial Atrophy Syndrome, 7 linear scleroderma of an extremity and 2 with mixed forms (linear and morphea). Electromyogram analysis indicated that all but one had asymmetric myopathic pattern in muscles underlying the linear streaks. Motor and sensory nerve conduction was also evaluated in upper and lower limbs and one presented a neurogenic pattern. Masticatory muscle testing showed a myopathic pattern in the atrophic face of 2 cases with head and face involvement.Conclusion: In our small series of LS patients, we found a surprising amount of muscle dysfunction by EMG. The muscle involvement may be possibly related to a secondary peripheral nerve involvement due to LS inflammation and fibrosis. Further collaborative studies to confirm these findings are needed.
dc.languageeng
dc.publisherBiomed Central Ltd.
dc.relationPediatric Rheumatology
dc.relation2.543
dc.relation0,729
dc.rightsAcesso aberto
dc.sourceWeb of Science
dc.subjectElectromyography
dc.subjectLinear scleroderma
dc.subjectMuscle
dc.subjectPeripheral nervous system
dc.titleA cross-sectional electromyography assessment in linear scleroderma patients
dc.typeArtículos de revistas


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