Processos de preparação de complexos fosfínicos de rutênio contendo íon picolinato e/ou diiminas e/ou bifosfinas em sua estrutura, complexos fosfínicos de Rutênio obtidos pelos referidos processos e seus usos.

dc.contributor	Universidade Estadual Paulista (Unesp)
dc.contributor	Universidade Federal de São Carlos (UFSCar)
dc.contributor	Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.date.accessioned	2014-09-02T13:14:17Z
dc.date.available	2014-09-02T13:14:17Z
dc.date.created	2014-09-02T13:14:17Z
dc.date.issued	2011-11-10
dc.identifier	http://hdl.handle.net/11449/109071
dc.identifier	INPI-WO2011137503.pdf
dc.description.abstract	The invention relates to the synthesis and characterisation of ruthenium(II) phosphine complexes containing picolinate and/or diimine and/or biphosphine ions and having an outstanding pharmacological activity for inhibiting the growth of tuberculosis mycobacteria. These complexes can first be used in the chemical industry, and in the medium and long term, in the pharmaceutical industry. The invention also describes how the activity against tuberculosis bacillus was determined, and how the toxicity of the complexes against macrophage cells within which the tuberculosis bacillus grows was assessed.
dc.language	por
dc.publisher	Instituto Nacional de Propriedade Industrial (INPI)
dc.rights	Acesso aberto
dc.source	Instituto Nacional de Propriedade Industrial (INPI)
dc.title	Processos de preparação de complexos fosfínicos de rutênio contendo íon picolinato e/ou diiminas e/ou bifosfinas em sua estrutura, complexos fosfínicos de Rutênio obtidos pelos referidos processos e seus usos.
dc.type	Patentes