Artículos de revistas
Systematic reviews showed insufficient evidence for clinical practice in 2004: What about in 2011? the next appeal for the evidence-based medicine age
Date
2013-08-01Registration in:
Journal of Evaluation in Clinical Practice, v. 19, n. 4, p. 633-637, 2013.
1356-1294
1365-2753
10.1111/j.1365-2753.2012.01877.x
WOS:000329303400010
2-s2.0-84881150396
8889393461577095
0260120486355934
3228294827229620
9490853654189131
8223546475724058
9276729087180415
9327504777606061
8003931926137460
7199562550978496
9465938306255342
4043953540121335
0000-0002-0090-8524
0000-0002-1573-4678
0000-0002-6977-4165
0000-0002-9362-1505
0000-0001-8055-5425
Author
Universidade Estadual Paulista (Unesp)
McMaster University
Institutions
Abstract
Rationale and aim The aims of the Cochrane systematic reviews are to make readily available and up-to-date information for clinical practice, offering consistent evidence and straightforward recommendations. In 2004, we evaluated the conclusions from Cochrane systematic reviews of randomized controlled trials in terms of their recommendations for clinical practice and found that 47.83% of them had insufficient evidence for use in clinical practice. We proposed to reanalyze the reviews to evaluate whether this percentage had significantly decreased. Methods A cross-sectional study of systematic reviews published in the Cochrane Library (Issue 7, 2011) was conducted. We randomly selected reviews across all 52 Cochrane Collaborative Review Groups. Results We analyzed 1128 completed systematic reviews. Of these, 45.30% concluded that the interventions studied were likely to be beneficial, of which only 2.04% recommended no further research. In total, 45.04% of the reviews reported that the evidence did not support either benefit or harm, of which 0.8% did not recommend further studies and 44.24% recommended additional studies; the latter has decreased from our previous study with a difference of 3.59%. Conclusion Only a small number of the Cochrane collaboration's systematic reviews support clinical interventions with no need for additional research. A larger number of high-quality randomized clinical trials are necessary to change the 'insufficient evidence' scenario for clinical practice illustrated by the Cochrane database. It is recommended that we should produce higher-quality primary studies in active collaboration and consultation with global scholars and societies so that this can represent a major component of methodological advance in this context. © 2012 John Wiley & Sons Ltd.
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