dc.contributorUniversidade Estadual de Campinas (UNICAMP)
dc.contributorColumbia University
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:26:07Z
dc.date.available2014-05-27T11:26:07Z
dc.date.created2014-05-27T11:26:07Z
dc.date.issued2011-11-10
dc.identifierActa Cirurgica Brasileira, v. 26, n. SUPPL. 2, p. 106-110, 2011.
dc.identifier0102-8650
dc.identifier1678-2674
dc.identifierhttp://hdl.handle.net/11449/72792
dc.identifier10.1590/S0102-86502011000800019
dc.identifierS0102-86502011000800019
dc.identifier2-s2.0-80555124917
dc.identifier2-s2.0-80555124917.pdf
dc.description.abstractPURPOSE: To present fundamental anatomical aspects and technical skills necessary to urethra and urinary bladder catheterization in female mice and rats. METHODS: Urethral and bladder catheterization has been widely utilized for carcinogenesis and cancer research and still remains very useful in several applications: from toxicological purposes as well as inflammatory and infectious conditions to functional aspects as bladder dynamics and vesicoureteral reflux, among many others. RESULTS: Animal models are in the center of translational research and those involving rodents are the most important nowadays due to several advantages including human reproducibility, easy handling and low cost. CONCLUSIONS: Although technical and anatomical pearls for rodent urethral and bladder access are presented as tackles to the advancement of lower urinary tract preclinical investigation in a broaden sight, restriction to female animals hampers the male microenvironment, demanding future advances.
dc.languageeng
dc.languagepor
dc.relationActa Cirúrgica Brasileira
dc.relation0.933
dc.relation0,395
dc.rightsAcesso aberto
dc.sourceScopus
dc.subjectAnatomy
dc.subjectRats
dc.subjectRodent diseases
dc.subjectUrinary tract
dc.subjectanimal anatomy
dc.subjectanimal experiment
dc.subjectbladder
dc.subjectbladder catheterization
dc.subjectcancer research
dc.subjectcarcinogenesis
dc.subjectcost benefit analysis
dc.subjectfemale
dc.subjectmouse
dc.subjectnonhuman
dc.subjectrat
dc.subjecttoxicity testing
dc.subjecturethra
dc.subjecturethral catheterization
dc.subjectvesicoureteral reflux
dc.subjectAnimals
dc.subjectFemale
dc.subjectMedical Illustration
dc.subjectMice
dc.subjectModels, Animal
dc.subjectReproducibility of Results
dc.subjectSex Factors
dc.subjectUrethra
dc.subjectUrinary Bladder
dc.subjectUrinary Catheterization
dc.titleAnatomical features of the urethra and urinary bladder catheterization in female mice and rats. An essential translational tool
dc.typeArtículos de revistas


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