The Neuropsychiatric Inventory-Clinician rating scale (NPI-C): Reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia

dc.contributorCopper Ridge Institute
dc.contributorJohns Hopkins University School of Medicine
dc.contributorNice-Sophia Antipolis University
dc.contributorMcGill Center for Studies in Aging
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorAthens Hospital
dc.contributorUniversity Hospital Dementia Research Unit
dc.contributorInstitute Privado Kremer
dc.contributorDINOG
dc.contributorUniversity of Rochester
dc.contributorMayo Clinic
dc.contributorUniversity of South Wales
dc.contributorJahn Ferenc Hospital
dc.contributorUniversity of California
dc.contributorJohns Hopkins Bayview
dc.date.accessioned2014-05-27T11:24:47Z
dc.date.available2014-05-27T11:24:47Z
dc.date.created2014-05-27T11:24:47Z
dc.date.issued2010-09-01
dc.identifierInternational Psychogeriatrics, v. 22, n. 6, p. 984-994, 2010.
dc.identifier1041-6102
dc.identifier1741-203X
dc.identifierhttp://hdl.handle.net/11449/71849
dc.identifier10.1017/S1041610210000876
dc.identifier2-s2.0-77957319896
dc.identifier2-s2.0-77957319896.pdf
dc.description.abstractBackground: Neuropsychiatric symptoms (NPS) affect almost all patients with dementia and are a major focus of study and treatment. Accurate assessment of NPS through valid, sensitive and reliable measures is crucial. Although current NPS measures have many strengths, they also have some limitations (e.g. acquisition of data is limited to informants or caregivers as respondents, limited depth of items specific to moderate dementia). Therefore, we developed a revised version of the NPI, known as the NPI-C. The NPI-C includes expanded domains and items, and a clinician-rating methodology. This study evaluated the reliability and convergent validity of the NPI-C at ten international sites (seven languages). Methods: Face validity for 78 new items was obtained through a Delphi panel. A total of 128 dyads (caregivers/patients) from three severity categories of dementia (mild = 58, moderate = 49, severe = 21) were interviewed separately by two trained raters using two rating methods: the original NPI interview and a clinician-rated method. Rater 1 also administered four additional, established measures: the Apathy Evaluation Scale, the Brief Psychiatric Rating Scale, the Cohen-Mansfield Agitation Index, and the Cornell Scale for Depression in Dementia. Intraclass correlations were used to determine inter-rater reliability. Pearson correlations between the four relevant NPI-C domains and their corresponding outside measures were used for convergent validity. Results: Inter-rater reliability was strong for most items. Convergent validity was moderate (apathy and agitation) to strong (hallucinations and delusions; agitation and aberrant vocalization; and depression) for clinician ratings in NPI-C domains. Conclusion: Overall, the NPI-C shows promise as a versatile tool which can accurately measure NPS and which uses a uniform scale system to facilitate data comparisons across studies. Copyright © 2010 International Psychogeriatric Association.
dc.languageeng
dc.relationInternational Psychogeriatrics
dc.relation2.261
dc.relation1,048
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectagitation
dc.subjectAlzheimer's disease
dc.subjectapathy
dc.subjectdementia
dc.subjectdepression
dc.subjectneuropsychiatric inventory
dc.subjectneuropsychiatric symptoms
dc.subjectadult
dc.subjectaged
dc.subjectaggression
dc.subjectBrief Psychiatric Rating Scale
dc.subjectcontrolled study
dc.subjectDelphi study
dc.subjectdelusion
dc.subjectdisease severity
dc.subjectdysphoria
dc.subjecteating disorder
dc.subjectface validity
dc.subjecthallucination
dc.subjecthuman
dc.subjectinterrater reliability
dc.subjectinterview
dc.subjectirritability
dc.subjectmajor clinical study
dc.subjectmental disease
dc.subjectmotor dysfunction
dc.subjectneuropsychiatric inventory clinician rating scale
dc.subjectphysician
dc.subjectrating scale
dc.subjectsleep
dc.subjectspeech disorder
dc.subjectvalidation study
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectAlzheimer Disease
dc.subjectApathy
dc.subjectCommunication
dc.subjectCross-Cultural Comparison
dc.subjectDelusions
dc.subjectDepressive Disorder
dc.subjectFemale
dc.subjectHallucinations
dc.subjectHumans
dc.subjectMale
dc.subjectMental Disorders
dc.subjectMental Status Schedule
dc.subjectNeuropsychological Tests
dc.subjectObserver Variation
dc.subjectPsychometrics
dc.subjectPsychomotor Agitation
dc.subjectReproducibility of Results
dc.subjectStatistics as Topic
dc.titleThe Neuropsychiatric Inventory-Clinician rating scale (NPI-C): Reliability and validity of a revised assessment of neuropsychiatric symptoms in dementia
dc.typeArtículos de revistas


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