Atenolol reduces salivary activity in pups of spontaneously hypertensive and normotensive rats treated during pregnancy and lactation

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:22:48Z
dc.date.available2014-05-27T11:22:48Z
dc.date.created2014-05-27T11:22:48Z
dc.date.issued2008-02-01
dc.identifierClinical and Experimental Hypertension, v. 30, n. 2, p. 133-141, 2008.
dc.identifier1064-1963
dc.identifier1525-6006
dc.identifierhttp://hdl.handle.net/11449/70294
dc.identifier10.1080/10641960801931923
dc.identifier2-s2.0-39749168317
dc.identifier6656433539493879
dc.identifier0000-0002-8159-4853
dc.description.abstractThe salivary activity in pups of spontaneously hypertensive rats (SHR) and Wistar (W) rats treated with atenolol during pregnancy, and lactation was evaluated. Atenolol's anti-hypertensive effect on the SHR rats was noticed from the beginning of treatment. Atenolol-treated SHR and Wistar rat pups showed a decrease in salivary gland weight, salivary flow, and protein concentration, with no alteration in salivary amylase activity. Atenolol's effect on salivary glands can interfere with oral health maintenance. Copyright © Informa Healthcare USA, Inc.
dc.languageeng
dc.relationClinical and Experimental Hypertension
dc.relation1.367
dc.relation0,507
dc.relation0,507
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectAtenolol
dc.subjectSalivary glands
dc.subjectSpontaneously hypertensive rats (SHR)
dc.subjectamylase
dc.subjectatenolol
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectantihypertensive activity
dc.subjectcontrolled study
dc.subjectenzyme activity
dc.subjectfemale
dc.subjecthealth
dc.subjecthypertension
dc.subjectlactation
dc.subjectmale
dc.subjectnonhuman
dc.subjectpregnancy
dc.subjectrat
dc.subjectsalivary gland
dc.subjectsalivation
dc.subjectAdrenergic beta-Antagonists
dc.subjectAmylases
dc.subjectAnimals
dc.subjectFemale
dc.subjectHypertension
dc.subjectLactation
dc.subjectMale
dc.subjectOrgan Size
dc.subjectOsmolar Concentration
dc.subjectPregnancy
dc.subjectPregnancy Complications, Cardiovascular
dc.subjectRats
dc.subjectRats, Inbred SHR
dc.subjectRats, Wistar
dc.subjectSaliva
dc.subjectSalivary Glands
dc.subjectSalivary Proteins
dc.titleAtenolol reduces salivary activity in pups of spontaneously hypertensive and normotensive rats treated during pregnancy and lactation
dc.typeArtículos de revistas


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