Amphibian secretions for drug discovery studies: A search for new antiparasitic and antifungal compounds

dc.contributorInstituto Adolfo Lutz (IAL)
dc.contributorInstituto Butantan
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:22:24Z
dc.date.available2014-05-27T11:22:24Z
dc.date.created2014-05-27T11:22:24Z
dc.date.issued2007-01-10
dc.identifierLetters in Drug Design and Discovery, v. 4, n. 1, p. 67-73, 2007.
dc.identifier1570-1808
dc.identifierhttp://hdl.handle.net/11449/69512
dc.identifier10.2174/157018007778992856
dc.identifierWOS:000242910300012
dc.identifier2-s2.0-33845967153
dc.identifier0458077399058762
dc.description.abstractThe antiparasitic and antifungal activities of nine amphibian skin secretions were studied in different in vitro models. Seven secretions presented a considerable antiprotozoan activity and one showed promising results against Candida sp. These results can be the basis for the development of new drugs, especially for neglected parasitic diseases. © 2007 Bentham Science Publishers Ltd.
dc.languageeng
dc.relationLetters in Drug Design and Discovery
dc.relation0.924
dc.relation0,247
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectAmphibians
dc.subjectAntimicrobial
dc.subjectLeishmania
dc.subjectPeptides
dc.subjectSecretions
dc.subjectTrypanosoma
dc.subjectamino acid oxidase
dc.subjectamphibian protein
dc.subjectantifungal agent
dc.subjectantiparasitic agent
dc.subjectbenznidazole
dc.subjectmeglumine antimonate
dc.subjectpentamidine
dc.subjectpyrimethamine
dc.subjectAmphibia
dc.subjectanimal cell
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectCandida
dc.subjectcontrolled study
dc.subjectdose response
dc.subjectdrug design
dc.subjectdrug effect
dc.subjectdrug research
dc.subjectenzyme activity
dc.subjectgrowth inhibition
dc.subjectmouse
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectskin secretion
dc.titleAmphibian secretions for drug discovery studies: A search for new antiparasitic and antifungal compounds
dc.typeArtículos de revistas


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