Behavioural alterations provoked by prolonged calcitonin administration in rats

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:20:41Z
dc.date.available2014-05-27T11:20:41Z
dc.date.created2014-05-27T11:20:41Z
dc.date.issued2003-07-01
dc.identifierRevista Brasileira de Toxicologia, v. 16, n. 1, p. 5-9, 2003.
dc.identifier1415-2983
dc.identifierhttp://hdl.handle.net/11449/67354
dc.identifier2-s2.0-0141573155
dc.description.abstractPresent work investigated the effect of prolonged administration of salmon calcitonin, a hormone secreted by parafollicular cells from thyroid, on behavioural parameters of rats. Animals received calcitonin sc, 100 mUI/100 g of body weight, three times a week, during 50 days. Behaviour was assessed utilizing an Open Field, Elevated Plus-Maze and Hole Board apparatus. Calcitonin treatment in rats seems to modify open field and elevated plus maze behaviour, suggesting emotionality and anxiety state alterations of the animals. These conditions can be provoked due to the direct calcitonin action on its receptors, even though we do not exclude an action mediated by tissue calcium level alterations.
dc.languageeng
dc.relationRevista Brasileira de Toxicologia
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectBehavior
dc.subjectCalcitonin
dc.subjectElevated-Plus-Maze
dc.subjectHole Board
dc.subjectOpen Field
dc.subjectRat
dc.subjectcalcitonin
dc.subjectanimal behavior
dc.subjectanimal experiment
dc.subjectbehavior
dc.subjectcontrolled study
dc.subjectemotionality
dc.subjectmale
dc.subjectmaze test
dc.subjectnonhuman
dc.subjectopen field behavior
dc.subjectrat
dc.subjectthyroid gland
dc.subjectthyroid parafollicular cell
dc.subjecttissue level
dc.subjectAnimalia
dc.titleBehavioural alterations provoked by prolonged calcitonin administration in rats
dc.typeArtículos de revistas


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