Artículos de revistas
Effects of glucose infusion on the endocrine, metabolic and cardiorespiratory responses to halothane anaesthesia of ponies
Fecha
1999-07-24Registro en:
Veterinary Record, v. 145, n. 4, p. 100-103, 1999.
0042-4900
10.1136/vr.145.4.100
WOS:000082051400008
2-s2.0-0033600471
4473260410099623
0000-0001-5312-9076
Autor
Universidade Estadual Paulista (Unesp)
University of Cambridge
Animal Health Trust
Institución
Resumen
Glucose was infused intravenously into six ponies during halothane anaesthesia, to evaluate its effect on their endocrine response to anaesthesia. The ponies were premedicated with acepromazine, and anaesthesia was induced with thiopentone and maintained with halothane in oxygen for two hours. Glucose was infused to maintain the plasma glucose concentration above 20 mmol/litre. Anaesthesia was associated with hypothermia, a decrease in haematocrit, hypotension, hyperoxaemia, respiratory acidosis and an increase in the plasma concentrations of lactate and arginine vasopressin. The concentration of β-endorphin in plasma increased transiently after 20 minutes but there were no changes in concentrations of adrenocorticotrophic hormone, dynorphin, cortisol or catecholamines. These data suggest that the glucose infusion attenuated the normal adrenal response of ponies to halothane anaesthesia.
Materias
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