Platelet activation in experimental arterial thrombosis.

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T03:47:06Z
dc.date.available2014-05-27T03:47:06Z
dc.date.created2014-05-27T03:47:06Z
dc.date.issued1987-12-01
dc.identifierBrazilian Journal of Medical and Biological Research, v. 20, n. 5, p. 611-613, 1987.
dc.identifier0100-879X
dc.identifierhttp://hdl.handle.net/11449/63830
dc.identifier2-s2.0-0023494435
dc.description.abstractPlatelet aggregates were studied in dogs with induced arterial thrombosis, by the method of Wu and Hoak. Blood was withdrawn from a jugular vein and from the femoral vein on the operated side 24 h after thrombus induction and immediately and 2 h after blood flow was restored by thrombectomy. Platelet activation was significant in dogs with obstructive arterial thrombosis and which tended to subside after thrombectomy. Activation or formation of platelet aggregates seemed to occur in the ischemic limb. It is suggested that this experimental model could be useful to test the action of anti-platelet drugs in vivo.
dc.languageeng
dc.relationBrazilian Journal of Medical and Biological Research
dc.relation1.492
dc.rightsAcesso restrito
dc.sourceScopus
dc.subjectanimal
dc.subjectblood
dc.subjectdog
dc.subjectfemoral artery
dc.subjectpathophysiology
dc.subjectthrombocyte aggregation
dc.subjectthrombosis
dc.subjectAnimal
dc.subjectDogs
dc.subjectFemoral Artery
dc.subjectPlatelet Aggregation
dc.subjectSupport, Non-U.S. Gov't
dc.subjectThrombosis
dc.titlePlatelet activation in experimental arterial thrombosis.
dc.typeArtículos de revistas


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