dc.contributor | Universidade de São Paulo (USP) | |
dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.contributor | Hosp Olhos Araraquara | |
dc.contributor | Penn State Coll Med | |
dc.date.accessioned | 2014-05-20T15:23:22Z | |
dc.date.available | 2014-05-20T15:23:22Z | |
dc.date.created | 2014-05-20T15:23:22Z | |
dc.date.issued | 2007-09-01 | |
dc.identifier | Acta Ophthalmologica Scandinavica. Oxford: Blackwell Publishing, v. 85, n. 6, p. 603-608, 2007. | |
dc.identifier | 1395-3907 | |
dc.identifier | http://hdl.handle.net/11449/34162 | |
dc.identifier | 10.1111/j.1600-0420.2007.00923.x | |
dc.identifier | WOS:000248922800004 | |
dc.identifier | WOS000248922800004.pdf | |
dc.description.abstract | Purpose: To compare the safety and anti-inflammatory efficacy of a single posterior subtenon injection of triamcinolone acetonide (TA) with prednisolone acetate 1% eyedrops after pars plana vitrectomy (PPV).Methods: the study included 40 consecutive phakic eyes of 40 patients undergoing PPV for non-clearing vitreous haemorrhage with attached retina (verified by echography), epiretinal membrane or macular hole. At the end of the surgical procedure, eyes were randomized to receive either a single posterior subtenon injection of TA (40 mg in 1 ml) plus sham eyedrops (prednisolone acetate 1% vehicle) postoperatively (group TA), or a posterior subtenon sham injection (1 ml balanced salt solution) plus prednisolone acetate 1% eyedrops postoperatively (group ED).Results: There was no difference in the severity of anterior chamber cell and flare between the two groups at any time-point during the study period (p > 0.05). Separate within-group analysis revealed a significant decrease in anterior chamber cell and flare from postoperative day 1 to postoperative days 7, 14 and 28 in both groups (p < 0.05). There was no difference in pain, photophobia, conjunctival erythema, ciliary flush or chemosis scores between the two groups at any time-point during the study period (p > 0.05). Steroid-induced intraocular hypertension was not observed in either group.Conclusions: A single posterior subtenon injection of TA can be as effective and safe as a 4-week regimen of prednisolone acetate 1% eyedrops in controlling intraocular inflammation after PPV. | |
dc.language | eng | |
dc.publisher | Blackwell Publishing | |
dc.relation | Acta Ophthalmologica Scandinavica | |
dc.rights | Acesso aberto | |
dc.source | Web of Science | |
dc.subject | drug delivery | |
dc.subject | inflammation | |
dc.subject | postoperative care | |
dc.subject | prednisolone | |
dc.subject | triamcinolone | |
dc.subject | vitrectomy | |
dc.subject | vitreous | |
dc.title | Anti-inflammatory efficacy of a single posterior subtenon injection of triamcinolone acetonide versus prednisolone acetate 1% eyedrops after pars plana vitrectomy | |
dc.type | Artículos de revistas | |