Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae

dc.contributorUniversidade Federal de São Paulo (UNIFESP)
dc.contributorUniversidade de São Paulo (USP)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:23:09Z
dc.date.available2014-05-20T15:23:09Z
dc.date.created2014-05-20T15:23:09Z
dc.date.issued2005-01-01
dc.identifierPhysiological Research. Prague 4: Acad Sciences Czech Republic, Inst Physiology, v. 54, n. 5, p. 557-564, 2005.
dc.identifier0862-8408
dc.identifierhttp://hdl.handle.net/11449/33989
dc.identifierWOS:000233101100012
dc.identifier8845835550637809
dc.identifier4977572416129527
dc.identifier0000-0002-4292-3298
dc.description.abstractIn this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 mu g of glucan by i.p. route, were assayed. In vivo mu-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.
dc.languageeng
dc.publisherAcad Sciences Czech Republic, Inst Physiology
dc.relationPhysiological Research
dc.relation1.324
dc.relation0,568
dc.rightsAcesso aberto
dc.sourceWeb of Science
dc.subjectbeta-glucan
dc.subjectIL-12
dc.subjectTNF-alpha
dc.subjectNK activity
dc.subjectfungicidal activity
dc.titleImmunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae
dc.typeArtículos de revistas


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