Genetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil

dc.contributorNihon Univ
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorJorge Vaitsmann Municipal Inst
dc.contributorUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T15:23:00Z
dc.date.available2014-05-20T15:23:00Z
dc.date.created2014-05-20T15:23:00Z
dc.date.issued2007-11-01
dc.identifierJournal of Veterinary Medical Science. Tokyo: Japan Soc Vet Sci, v. 69, n. 11, p. 1145-1154, 2007.
dc.identifier0916-7250
dc.identifierhttp://hdl.handle.net/11449/33864
dc.identifier10.1292/jvms.69.1145
dc.identifierWOS:000251744200007
dc.identifierWOS000251744200007.pdf
dc.identifier4098511928890053
dc.identifier9477933792138174
dc.description.abstractTo investigate the genetic characteristics of phosphoprotein (P) and matrix protein (M) genes of variable rabies virus (RV) prevalent in Brazil, the authors genetically characterized the P and M genes from 30 Brazilian RV field isolates. Phylogenetic analysis based on the P and M genes revealed the presence of six RV variants that consisted primarily of three insectivorous bats, the vampire bat, dog and fox in Brazil. Specific amino acid substitutions corresponding to these phylogenetic lineages were observed, with ASP(42) and GlU(62) in the P protein found to be characteristic of Brazilian chiroptera- and carnivora-related RVs, respectively. Amino acid sequence motifs predicted to associate with a viral function in the P and M proteins were conserved among Brazilian RV variants.
dc.languageeng
dc.publisherJapan Soc Vet Sci
dc.relationJournal of Veterinary Medical Science
dc.relation0.803
dc.relation0,459
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectBrazil
dc.subjectgenetic analysis
dc.subjectmatrix protein
dc.subjectphosphoprotein
dc.subjectrabies virus
dc.titleGenetic analysis of phosphoprotein and matrix protein of rabies viruses isolated in Brazil
dc.typeArtículos de revistas


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