dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:22:07Z
dc.date.available2014-05-20T15:22:07Z
dc.date.created2014-05-20T15:22:07Z
dc.date.issued1997-01-01
dc.identifierRenal Failure. New York: Marcel Dekker Inc., v. 19, n. 2, p. 253-257, 1997.
dc.identifier0886-022X
dc.identifierhttp://hdl.handle.net/11449/33177
dc.identifier10.3109/08860229709026285
dc.identifierWOS:A1997WQ40600012
dc.identifier2-s2.0-0030938725
dc.identifier5496411983893479
dc.identifier0000-0003-4979-4836
dc.description.abstractAcute renal failure (ARF) is a frequent complication in hospitalized patients and is strongly related to increase in mortality. In order to analyze the clinical outcome and the prognostic factors in hospital-acquired ARF a prospective study was performed. Data from 200 patients with established ARF during the period of January 1987 through July 1990 were collected. The incidence of ARF was 4.9/1000 admissions. Renal ischemia (50%) and nephrotoxic drugs (21%) were the main etiologic factors. The histologic study done in 43 patients showed: acute tubular necrosis (53%), tubular hydropic degeneration (16%), glomerulopathies (16%), and other lesions (15%). Dialysis therapy was performed in 101 patients. The mortality rate was 46.5% and the most important causes of death were. sepsis (38%), respiratory failure (19%), and multiple organ failure (11%). Higher mortality was observed in oliguric patients (62.9%) than nonoliguric (34.5%) (p < 0.05) and in ischemic renal failure (56.7%) when compared to nephrotoxic renal failure (14.7%) (p < 0.05). As primary cause of death was not associated to the acute renal failure, conclude that acute renal failure is an important marker of the gravity of the underlying disease and not the cause of death.
dc.languageeng
dc.publisherMarcel Dekker Inc
dc.relationRenal Failure
dc.relation1.440
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectacute renal failure
dc.subjectclinical outcome
dc.subjectmortality
dc.subjectprognosis
dc.titleAcute renal failure: Clinical outcome and causes of death
dc.typeArtículos de revistas


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