dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.contributor | Universidade de São Paulo (USP) | |
dc.date.accessioned | 2014-05-20T15:21:06Z | |
dc.date.available | 2014-05-20T15:21:06Z | |
dc.date.created | 2014-05-20T15:21:06Z | |
dc.date.issued | 2007-04-01 | |
dc.identifier | Spectrochimica Acta Part A-molecular and Biomolecular Spectroscopy. Oxford: Pergamon-Elsevier B.V., v. 66, n. 4-5, p. 1171-1174, 2007. | |
dc.identifier | 1386-1425 | |
dc.identifier | http://hdl.handle.net/11449/32287 | |
dc.identifier | 10.1016/j.saa.2006.06.003 | |
dc.identifier | WOS:000245480400059 | |
dc.description.abstract | A new palladium(II) complex with methionine sulfoxide was synthesized and characterized by a set of chemical and spectroscopic techniques. Elemental and mass spectrometry analyses of the solid complex fit to the composition [Pd(C5H10NO3S)(2)]center dot H2O. C-13 NMR, [H-1-N-15] NMR and infrared spectra indicate coordination of the amino acid to Pd(II) through the carboxylate and amino groups in a square planar geometry. The complex is soluble in water.Biological activity was evaluated by cytotoxic analysis using HeLa cells. Determination of cell death was assessed using a tetrazolium salt colorimetric assay, which reflects the cells viability. After incubation for 48 h, 20% of cell death was achieved at a concentration of 200 mu mol L-1 of the complex. (c) 2006 Elsevier B.V. All rights reserved. | |
dc.language | eng | |
dc.publisher | Elsevier B.V. | |
dc.relation | Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy | |
dc.relation | 2.880 | |
dc.relation | 0,648 | |
dc.rights | Acesso restrito | |
dc.source | Web of Science | |
dc.subject | palladium(II) | |
dc.subject | methionine sulfoxide | |
dc.subject | infrared spectroscopy | |
dc.subject | N-15 NMR | |
dc.subject | antitumor | |
dc.subject | cytotoxicity | |
dc.title | Synthesis, spectroscopic characterization and biological analysis of a new palladium(II) complex with methionine sulfoxide | |
dc.type | Artículos de revistas | |