Voltammetric sensor for amoxicillin determination in human urine using polyglutamic acid/glutaraldehyde film

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T14:19:17Z
dc.date.available2014-05-20T14:19:17Z
dc.date.created2014-05-20T14:19:17Z
dc.date.issued2008-08-12
dc.identifierSensors and Actuators B-chemical. Lausanne: Elsevier B.V. Sa, v. 133, n. 2, p. 398-403, 2008.
dc.identifier0925-4005
dc.identifierhttp://hdl.handle.net/11449/25818
dc.identifier10.1016/j.snb.2008.02.045
dc.identifierWOS:000259268600008
dc.identifier0000-0002-2296-1393
dc.description.abstractA voltammetric sensor for determination of amoxicillin (AMX) was developed based on a glutaraldehyde cross-linked polyglutamic acid modified glassy carbon electrode. The proposed method is based on pre-concentration of AMX by cathodic accumulation as its oxidative product before being determined indirectly at potential as low as +0.23 V by square wave voltammetry. Linear response range, sensitivity and limit of detection were 2.0-25.0, 1.06 and 0.9.2 mu mol L-1, respectively, for AMX in 0.1 mol L-1 acetate buffer pH 5.2, pre-accurnulation time of 60s and accumulation potential of +1.0V. It was demonstrated that the glassy carbon electrode modified with PGA/GLU could be used for AMX determination in human urine without any separation step. (C) 2008 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherElsevier B.V. Sa
dc.relationSensors and Actuators B: Chemical
dc.relation5.667
dc.relation1,406
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectsensor voltammetric
dc.subjectfilms of polyglutamic acid
dc.subjectamoxicillin
dc.subjecthuman urine
dc.titleVoltammetric sensor for amoxicillin determination in human urine using polyglutamic acid/glutaraldehyde film
dc.typeArtículos de revistas


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