dc.contributor | Universidade Estadual Paulista (Unesp) | |
dc.date.accessioned | 2014-05-20T14:18:58Z | |
dc.date.available | 2014-05-20T14:18:58Z | |
dc.date.created | 2014-05-20T14:18:58Z | |
dc.date.issued | 2001-04-01 | |
dc.identifier | Journal of the Brazilian Chemical Society. Sociedade Brasileira de Química, v. 12, n. 2, p. 202-207, 2001. | |
dc.identifier | 0103-5053 | |
dc.identifier | http://hdl.handle.net/11449/25711 | |
dc.identifier | 10.1590/S0103-50532001000200013 | |
dc.identifier | S0103-50532001000200013 | |
dc.identifier | S0103-50532001000200013.pdf | |
dc.identifier | 0072173018005712 | |
dc.identifier | 0000-0002-2296-1393 | |
dc.description.abstract | Clotrimazol é reduzido em eletrodo de mercúrio em tampão fosfato pH > 6 através de um processo reversível de um elétron. O processo eletródico apresenta forte efeito de adsorção, o qual pode ser minimizado na presença de Triton X-100. Clotrimazol pode ser determinado em níveis de 50 ng mL-1 quando pré-acumulado durante 3 min à -0,20 V. O método proposto foi aplicado para determinação do fármaco em formulação comercial. | |
dc.description.abstract | The reduction of clotrimazole at a mercury electrode, in phosphate buffer, pH>6, involves a reversible one-electron process. The electrochemical process presents a large contribution from adsorption effects. For the differential pulse polarographic determination the addition of Triton X-100 is recommended. Clotrimazole can be determined by cathodic stripping voltammetry at 50 ng mL-1 level when pre-accumulated for 3 min at an accumulation potential of -0.20 V. The proposed method is applied successfully for the determination of clotrimazole in a commercial formulation. | |
dc.language | eng | |
dc.publisher | Sociedade Brasileira de Química | |
dc.relation | Journal of the Brazilian Chemical Society | |
dc.relation | 1.444 | |
dc.relation | 0,357 | |
dc.rights | Acesso aberto | |
dc.source | SciELO | |
dc.subject | clotrimazole | |
dc.subject | cyclic voltammetry | |
dc.subject | differential pulse polarography | |
dc.subject | cathodic stripping voltammetry | |
dc.title | Electrochemical reduction and cathodic stripping voltammetric determination of clotrimazole | |
dc.type | Artículos de revistas | |