Spectrophotometric determination of cefaclor in pharmaceutical preparations

dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T14:18:56Z
dc.date.available2014-05-20T14:18:56Z
dc.date.created2014-05-20T14:18:56Z
dc.date.issued1999-04-01
dc.identifierQuímica Nova. Sociedade Brasileira de Química, v. 22, n. 2, p. 201-204, 1999.
dc.identifier0100-4042
dc.identifierhttp://hdl.handle.net/11449/25705
dc.identifier10.1590/S0100-40421999000200011
dc.identifierS0100-40421999000200011
dc.identifier0000-0002-2296-1393
dc.description.abstractA simple spectrophotometric method is proposed for the determination of cefaclor. The method involves alkaline hydrolysis of the drug in ammonia buffer solution at pH 10 to yield diketopiperazine-2,5-dione derivative and subsequent measurement at 340 nm. Beer's law is obeyed in the concentration range 1.8 - 55 mg/mL. The proposed method was successfully applied to the determination of cefaclor in pharmaceutical formulations.
dc.languageeng
dc.publisherSociedade Brasileira de Química
dc.relationQuímica Nova
dc.relation0.646
dc.relation0,255
dc.rightsAcesso aberto
dc.sourceSciELO
dc.subjectcefaclor
dc.subjecthydrolysis
dc.subjectpharmaceuticals
dc.titleSpectrophotometric determination of cefaclor in pharmaceutical preparations
dc.typeArtículos de revistas


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