dc.contributorUniversidade Federal de Uberlândia (UFU)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T14:03:07Z
dc.date.available2014-05-20T14:03:07Z
dc.date.created2014-05-20T14:03:07Z
dc.date.issued2008-07-01
dc.identifierMolecular and Biochemical Parasitology. Amsterdam: Elsevier B.V., v. 160, n. 1, p. 70-73, 2008.
dc.identifier0166-6851
dc.identifierhttp://hdl.handle.net/11449/22245
dc.identifier10.1016/j.molbiopara.2008.03.009
dc.identifierWOS:000257024600009
dc.identifier2307201085881971
dc.description.abstractEsterases are a group of enzymes that are reportedly associated with acaricide resistance in Riphicephallus (Boophilus) microplus. A comparative analysis was made of the esterase patterns in malathion and deltamethrin-sensitive, tolerant and resistant tick groups, using non-denaturing polyacrylamide gel electrophoresis. Electrophoretical profiles revealed four bands of esterase activity against alpha-naphthyl acetate; which were dubbed EST-1 to EST-4. The EST-3 and EST-4 were detected in all strains and were classified as carboxylesterases (CaEs). The EST-2, classified as an acetylcholinesterase (AChE), was detected in all groups, but its staining intensity increased from susceptible to resistant groups, indicating an altered production according to the degree of resistance. EST-1, which was also classified as an AChE, was detected exclusively in tolerant and resistant groups to both acaricides, but displayed greater activity in the malathion-resistant group. These data suggest that these AChEs may represent an important detoxification strategy developed to overcome the effects of acaricides. (C) 2008 Elsevier B.V. All rights reserved.
dc.languageeng
dc.publisherElsevier B.V.
dc.relationMolecular and Biochemical Parasitology
dc.relation1.744
dc.relation1,109
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectacaricide resistance
dc.subjectAcetylcholinesterase
dc.subjectCarboxylesterase
dc.subjectcattle tick
dc.titleEsterase enzymes involved in pyrethroid and organophosphate resistance in a Brazilian population of Riphicephallus (Boophilus) microplus (Acari, Ixodidae)
dc.typeArtículos de revistas


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