dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:48:01Z
dc.date.available2014-05-20T13:48:01Z
dc.date.created2014-05-20T13:48:01Z
dc.date.issued2008-06-01
dc.identifierMycopathologia. Dordrecht: Springer, v. 165, n. 6, p. 355-365, 2008.
dc.identifier0301-486X
dc.identifierhttp://hdl.handle.net/11449/17113
dc.identifier10.1007/s11046-008-9091-6
dc.identifierWOS:000256091200001
dc.identifier3720489366427955
dc.identifier3320327570429539
dc.identifier0000-0003-1515-702X
dc.identifier0000-0002-8003-4109
dc.description.abstractThe mycelia-to-yeast (M-Y) transition, thermal tolerance and virulence profiles were evaluated for nine isolates of Paracoccidioides brasiliensis, including samples from two of the three recently discovered cryptic species, as well as their relation to the partial sequence and transcription of the hsp70 gene. The isolates Bt84 and T10 (from PS2 species) took more time to convert to yeast form and presented elongated yeast cells at 36 degrees C. Arthroconidia production was also observed during the M-Y transition for some isolates. Our data confirm that the hsp70 transcription may be associated with thermal tolerance, but this does not seem to be directly related to high virulence profiles. The partial sequencing of this gene allowed the separation of our isolates into two clusters that correspond to the two sympatric cryptic species occurring in an area hyperendemic for PCM (Botucatu, SP, Brazil).
dc.languageeng
dc.publisherSpringer
dc.relationMycopathologia
dc.relation1.476
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectcryptic species
dc.subjectdimorphism
dc.subjecthsp70 transcription
dc.subjectParacoccidioides brasiliensis
dc.titleDimorphism, thermal tolerance, virulence and Heat shock protein 70 transcription in different isolates of Paracoccidioides brasiliensis
dc.typeArtículos de revistas


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