Artículos de revistas
Compromised Primary Implant Stability
Fecha
2012-09-01Registro en:
Journal of Craniofacial Surgery. Philadelphia: Lippincott Williams & Wilkins, v. 23, n. 5, p. E524-E528, 2012.
1049-2275
10.1097/SCS.0b013e31825b3863
WOS:000309547200059
1566928219828056
Autor
Univ Ctr Araraquara UNIARA
Universidade Estadual Paulista (Unesp)
Institución
Resumen
The aim of this study was to evaluate implants installed with compromised primary stability associated or not with polylactide and polyglycolide copolymer (PLA/PGA). Two 0.4-mm overdrilled defects (3 mm in diameter and 6 mm long) were produced in the right tibia of 25 rabbits. Half of the defects were left untreated, and the other half was filled with PLA/PGA. Implants of 2.6 mm in diameter and 6 mm long were placed into all defects. Animals were killed at 5, 15, 40, and 60 postoperative days, and biomechanical analysis (torque-reverse), histomorphometry, and immunohistochemistry (osteoprotegerin, receptor activator of NFJB ligand [RANKL], osteocalcin, and collagen-1 [ COL- I] staining) were performed. All the implants achieved osseointegration. There were no statistically significant differences in the torque-reverse and in linear contact extension between bone tissue and implant surface and no statistically significant difference in osteoprotegerin, RANKL, osteocalcin, and collagen-1 expression between the studied groups in all studied periods (P > 0.05). We can conclude that osseointegration can occur in compromised primary implant stability situations, and the addition of PLA/PGA did not improve the osseointegration process in this experimental model.