Artículos de revistas
Low-level laser therapy on the treatment of oral and cutaneous pemphigus vulgaris: case report
Fecha
2012-09-01Registro en:
Lasers In Medical Science. London: Springer London Ltd, v. 27, n. 5, p. 1103-1106, 2012.
0268-8921
10.1007/s10103-012-1101-8
WOS:000307406500031
2543633050941005
Autor
Universidade Estadual Paulista (Unesp)
NUPEN Res & Educ Ctr Photo Therapy Hlth Sci
Institución
Resumen
Pemphigus vulgaris is a chronic autoimmune mucocutaneous disease that initially is manifested by painful intraoral erosions and ulcers which spread to other mucosa and the skin, generally more than 5 months after oral lesion manifestation. The treatment consists of prednisone alone or in combination with an immunosuppressive agent, and the clinical response is perceived within 2 to 4 weeks. Low-level laser therapy has been effective in accelerating the healing of injured tissue, thus inducing cell proliferation and increasing ATP, nucleic acid, and collagen synthesis. We reported two cases of pemphigus vulgaris that received systemic treatment associated with low-level laser therapy for oral and cutaneous lesions. We observed prompt analgesic effect in oral lesions and accelerated healing of oral and cutaneous wounds. Therefore, the present report suggests LLLT as a noninvasive technique that should be considered as an adjuvant therapy in oral and skin disorders in patients with PV.