Prospective study for the development of emulsion systems containing natural oil products

dc.contributorUniversidade Federal do Rio Grande do Norte (UFRN)
dc.contributorUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:24:54Z
dc.date.available2014-05-20T13:24:54Z
dc.date.created2014-05-20T13:24:54Z
dc.date.issued2012-07-01
dc.identifierJournal of Drug Delivery Science and Technology. Paris: Editions Sante, v. 22, n. 4, p. 367-372, 2012.
dc.identifier1773-2247
dc.identifierhttp://hdl.handle.net/11449/7844
dc.identifierWOS:000310047500015
dc.identifier9114495952533044
dc.description.abstractCopaiba oil, when used as anti-inflammatory and anti-infective agent, presents two major problems: i) low absorption and bioavailability and ii) an unpleasant taste. Once an appropriate emulsion was achieved, the samples were prepared using different surfactant binary mixtures to obtain a range of HLB values between 4.5 and 16.5. The HLB value of copaiba oil was 14.8; this system has been stable for more than one year, and the pseudo-ternary diagrams were useful to describe the component proportions. These results indicated that the copaiba oil emulsion might be a promising vehicle for topical delivery of drugs and active cosmetic ingredients.
dc.languageeng
dc.publisherEditions Sante
dc.relationJournal of Drug Delivery Science and Technology
dc.relation2.297
dc.relation0,517
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectEmulsion
dc.subjectCopaiba oil
dc.subjectHydrophilic-lipophilic balance
dc.subjectPseudo-ternary phase diagram
dc.subjectStability analysis
dc.titleProspective study for the development of emulsion systems containing natural oil products
dc.typeArtículos de revistas


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