dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade Federal do Paraná (UFPR)
dc.contributorUniversidade Federal de São Carlos (UFSCar)
dc.contributorUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:23:03Z
dc.date.available2014-05-20T13:23:03Z
dc.date.created2014-05-20T13:23:03Z
dc.date.issued2009-10-01
dc.identifierCurrent Analytical Chemistry. Sharjah: Bentham Science Publ Ltd, v. 5, n. 4, p. 303-310, 2009.
dc.identifier1573-4110
dc.identifierhttp://hdl.handle.net/11449/6879
dc.identifier10.2174/157341109789077759
dc.identifierWOS:000271373600002
dc.description.abstractCopper(II) hexacyanoferrate(III) (CuHCF) modified carbon paste electrode was used for the electroanalytical determination of dipyrone and acetaminophen in pharmaceutical preparations by cyclic voltammetry. Several parameters were investigated for the optimization of the sensor such as composition of the electrode, electrolytic solution, effect of pH, scan rate of potential and interference. The best conditions were found for an electrode composition in mass of 20% CuHCF, 55% graphite and 25% mineral oil in acetate buffer containing 0.05 mol L(-1) of NaCl. The analytical curve was linear in the dipyrone and acetaminophen concentration ranged from 1.25 x 10(-5) mol L(-1) to 1.23 x 10(-3) and 2.84 x 10(-4) to 2.59 x 10(-3) mol L(-1) respectively, being successfully applied to the determination of dipyrone and acetaminophen in pharmaceutical preparations. The CuHCF modified carbon paste electrode presented comparable results to those obtained using iodimetry and ultraviolet spectrophotometry methods, respectively.
dc.languageeng
dc.publisherBentham Science Publ Ltd
dc.relationCurrent Analytical Chemistry
dc.relation1.000
dc.relation0,274
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectModified carbon paste electrode
dc.subjectCopper(II) hexacyanoferrate(III)
dc.subjectVoltammetric determination
dc.subjectAnalgesics
dc.subjectPharmaceutical preparations
dc.titleDetermination of Analgesics (Dipyrone and Acetaminophen) in Pharmaceutical Preparations by Cyclic Voltammetry at a Copper(II) Hexacyanoferrate(III) Modified Carbon Paste Electrode
dc.typeArtículos de revistas


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