dc.contributorUniversidade Estadual Paulista (Unesp)
dc.contributorUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-20T13:18:25Z
dc.date.available2014-05-20T13:18:25Z
dc.date.created2014-05-20T13:18:25Z
dc.date.issued2010-02-01
dc.identifierJournal of Animal Science. Champaign: Amer Soc Animal Science, v. 88, n. 2, p. 435-441, 2010.
dc.identifier0021-8812
dc.identifierhttp://hdl.handle.net/11449/4508
dc.identifier10.2527/jas.2009-2174
dc.identifierWOS:000274040700003
dc.identifier7445254960858159
dc.identifier5866981114947883
dc.description.abstractThe aim of this study was to analyze LEP and DGAT1 gene polymorphisms in 3 Nelore lines selected for growth and to evaluate their effects on growth and carcass traits. Traits analyzed were birth, weaning, and yearling weight, rump height, LM area, backfat thickness, and rump fat thickness obtained by ultrasound. Two SNP in the LEP gene [LEP 1620(A/G) and LEP 305(T/C)] and the K232A mutation in the DGAT1 gene were analyzed. The sample consisted of 357 Nelore heifers from 2 lines selected for yearling weight and a control line, established in 1980, at the Estacao Experimental de Zootecnia de Sertaozinho (Sertaozinho, Brazil). Three genotypes were obtained for each marker. Differences in allele frequencies among the 3 lines were only observed for the DGAT1 K232A polymorphism, with the frequency of the A allele being greater in the control line than in the selected lines. The DGAT1 K232A mutation was associated only with rump height, whereas LEP 1620(A/G) was associated with weaning weight and LEP 305(T/C) with birth weight and backfat thickness. However, more studies, with larger data sets, are necessary before these makers can be used for marker-assisted selection.
dc.languageeng
dc.publisherAmer Soc Animal Science
dc.relationJournal of Animal Science
dc.relation1.711
dc.relation0,848
dc.rightsAcesso restrito
dc.sourceWeb of Science
dc.subjectBos indicus
dc.subjectMolecular marker
dc.subjectproductive trait
dc.subjectquantitative trait locus
dc.titleAssessment of DGAT1 and LEP gene polymorphisms in three Nelore (Bos indicus) lines selected for growth and their relationship with growth and carcass traits
dc.typeArtículos de revistas


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