Canine rabies in Rio Grande do Sul caused by an insectivorous bat rabies virus variant

dc.contributorpt-BR
dc.creatorBatista, Helena Beatriz de Carvalho Ruthner
dc.creatorCaldas, Eduardo
dc.creatorJunqueira, Dennis Malettich
dc.creatorTeixeira, Thais Fumaco
dc.creatorFerreira, José Carlos
dc.creatorSilva, Juliana Reis
dc.creatorRosa, Julio César de Almeida
dc.creatorRoehe, Paulo Michel
dc.date2018-03-30
dc.date.accessioned2018-11-07T22:07:45Z
dc.date.available2018-11-07T22:07:45Z
dc.identifierhttps://seer.ufrgs.br/ActaScientiaeVeterinariae/article/view/16414
dc.identifier10.22456/1679-9216.16414
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/2193154
dc.descriptionRabies is caused by rabies virus (RV), a RNA virus member of the Lyssavirus genus, family Rhabdoviridae. The aim of this study was to determine antigenic characteristics of a rabies virus isolate (RV183-07) recovered from a stray bitch that died of rabies and to infer the most likely source of contamination, since no urban rabies has been reported in the area in more than 20 years. The virus was identified by direct immunofluorescence and multiplied by one passage in mice. The antigenic profile of the isolate was determined with a panel of monoclonal antibodies to lyssavirus antigens on infected brain tissues. A fragment of the viral genome corresponding to the nucleoprotein (N) gene was submitted to reverse transcription/polymerase chain reaction and the amplicon obtained was subjected to restriction enzyme analysis. A 303 base pair fragment of the N gene was cloned, sequenced and compared to other RV sequences available at Genbank. The isolate RV183-07 displayed antigenic and genomic characteristics of rabies virus variants whose natural reservoir is the non-hematophagous bat Tadarida brasiliensis. Therefore, the most likely source of contamination of the bitch was an incidental contact with an infected bat of that species, common inhabitants of the area. In view of that, the status of “urban rabies-free” of the area was not compromised.pt-BR
dc.formatapplication/pdf
dc.languagepor
dc.publisherUniversidade Federal do Rio Grande do Sulen-US
dc.relationhttps://seer.ufrgs.br/ActaScientiaeVeterinariae/article/view/16414/9646
dc.rightsDireitos autorais 2018 Helena Beatriz de Carvalho Ruthner Batista, Eduardo Caldas, Dennis Malettich Junqueira, Thais Fumaco Teixeira, José Carlos Ferreira, Juliana Reis Silva, Julio César de Almeida Rosa, Paulo Michel Roehept-BR
dc.rightshttp://creativecommons.org/licenses/by/4.0pt-BR
dc.sourceActa Scientiae Veterinariae; v. 37, n. 4 (2009); 371-374en-US
dc.sourceActa Scientiae Veterinariae; v. 37, n. 4 (2009); 371-374pt-BR
dc.source1679-9216
dc.subjectPatologia Animalpt-BR
dc.subjectRaiva; Variantes; Raiva canina; Raiva urbana; Raiva em morcego insetívoro; Diagnósticopt-BR
dc.titleCanine rabies in Rio Grande do Sul caused by an insectivorous bat rabies virus variantpt-BR
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.coveragept-BR
dc.coveragept-BR
dc.coveragept-BR


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