Chlamydia trachomatis infection in infertile and pregnant women in southern Brazil

dc.contributorFIPE- HCPAen-US
dc.creatorGomez, Deborah Beltrami
dc.creatorMontenegro, Ivan Sereno
dc.creatorBaade, Guilherme Rezende
dc.creatorTerraciano, Paula Barros
dc.creatorSchneider, Raquel de Almeida
dc.creatorGotardi, Débora Helena Zanini
dc.creatorCardoso, Victória Furquim dos Santos
dc.creatorPassos, Eduardo Pandolfi
dc.date2016-10-21
dc.date.accessioned2018-11-07T18:54:33Z
dc.date.available2018-11-07T18:54:33Z
dc.identifierhttps://seer.ufrgs.br/hcpa/article/view/65188
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/2174809
dc.descriptionIntroduction: Chlamydia trachomatis (CT) is the most prevalent sexually transmitted bacterial infection, affecting mainly young, sexually active women. Untreated infection may lead to reproductive complications due to tubal damage. Infections during pregnancy may cause preterm labor, low birth weight, perinatal death, and neonatal conjunctivitis and pneumonia. There are few data on CT infection in Brazil. The aim of this study was to determine CT prevalence in infertile and pregnant women.Methods: A cross-sectional study included 77 infertile and 60 asymptomatic pregnant women. First-void urine was tested for CT using PCR (Polymerase Chain Reaction). Blood samples were collected for CT IgG antibodies testing using indirect immunofluorescence. A questionnaire about medical, gynecological, and sexual history was completed by all participants.Results: We found statistically similar prevalence of PCR and IgG antibodies between the groups. There was a 61% prevalence of CT IgG antibodies in infertile women and 56.7% in pregnant women. PCR was positive in only one (1.3%) infertile woman and in none pregnant women.Conclusion: There is a high prevalence of CT IgG antibody in Brazilian pregnant and infertile women, but we found a low prevalence of positive PCR in the urine samples. CT antibodies were associated with sexual behavior and smoking.Keywords: Chlamydia trachomatis, Chlamydia infections, prevalence, nucleic acid amplification techniques; infertility, female; fluorescent antibody techniqueen-US
dc.formatapplication/pdf
dc.languageeng
dc.publisherHCPA/FAMED/UFRGSen-US
dc.relationhttps://seer.ufrgs.br/hcpa/article/view/65188/pdf
dc.rightsDireitos autorais 2016 Clinical and Biomedical Researchpt-BR
dc.sourceClinical & Biomedical Research; v. 36, n. 3 (2016)en-US
dc.sourceClinical and Biomedical Research; v. 36, n. 3 (2016)pt-BR
dc.source2357-9730
dc.source0101-5575
dc.subjectMedicine; Gynecology; Human Reproductionen-US
dc.subjectChlamydia trachomatis; Chlamydia infections; prevalence; Nucleic Acid Amplification Techniques; Infertility, female; Fluorescent Antibody Techniqueen-US
dc.subjecten-US
dc.titleChlamydia trachomatis infection in infertile and pregnant women in southern Brazilen-US
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeAvaliado por Parespt-BR
dc.typePeer-reviewed Articleen-US


Este ítem pertenece a la siguiente institución