A silica supported tricarbocyanine based pH nanosensor with a large Stokes shift and a near infrared fluorescence response: performance in vitro and in live cells

dc.creatorToum Terrones, Yamili
dc.creatorColuccio Leskow, Federico
dc.creatorBordoni, Andrea Veronica
dc.creatorAcebedo, Sofía Lorena
dc.creatorSpagnuolo, Carla Cecilia
dc.creatorWolosiuk, Alejandro
dc.date.accessioned2018-04-05T17:27:38Z
dc.date.available2018-04-05T17:27:38Z
dc.date.created2018-04-05T17:27:38Z
dc.date.issued2017-05
dc.identifierToum Terrones, Yamili; Coluccio Leskow, Federico; Bordoni, Andrea Veronica; Acebedo, Sofía Lorena; Spagnuolo, Carla Cecilia; et al.; A silica supported tricarbocyanine based pH nanosensor with a large Stokes shift and a near infrared fluorescence response: performance in vitro and in live cells; Royal Society of Chemistry; Journal of Materials Chemistry B; 5; 5-2017; 4031-4034
dc.identifier2050-7518
dc.identifierhttp://hdl.handle.net/11336/40911
dc.identifierCONICET Digital
dc.identifierCONICET
dc.description.abstractWe report the synthesis of a near-infrared (NIR) fluorescent pHprobe with a remarkable Stokes shift reported (∼ 135 nm) basedon a tricarbocyanine (Cy-PIP). The fluorescent molecule wasanchored to SiO2 nanoparticles (Cy-PIP@SiO2) and is capable ofmonitoring pH changes within the physiological range (pH 6-8).The Cy-PIP@SiO2 nanoparticles were succesfully internalized byHeLa cells as shown by fluorescence confocal microscopy, whileflow cytometry revealed pH fluctuations during the endocytic pathway.
dc.languageeng
dc.publisherRoyal Society of Chemistry
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1039/C7TB00622E
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2017/TB/C7TB00622E
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNanoparticles
dc.subjectCyanines
dc.subjectFluorescence
dc.subjectPh
dc.titleA silica supported tricarbocyanine based pH nanosensor with a large Stokes shift and a near infrared fluorescence response: performance in vitro and in live cells
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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