Artículos de revistas
Conformation and stereodynamics of 1,2-diaryltetrahydropyrimidine and of its five- and seven-membered ring analogs
Fecha
2011-11Registro en:
Díaz, Jimena Estela; Gruber, Nadia; Lunazzi, Lodovico; Mazzanti, Andrea; Orelli, Liliana Raquel; Conformation and stereodynamics of 1,2-diaryltetrahydropyrimidine and of its five- and seven-membered ring analogs; Elsevier; Tetrahedron; 67; 47; 11-2011; 9129-9133
0040-4020
Autor
Díaz, Jimena Estela
Gruber, Nadia
Lunazzi, Lodovico
Mazzanti, Andrea
Orelli, Liliana Raquel
Resumen
The 1-(2-nitrophenyl)-2-(2-methylphenyl)-1,4,5,6-tetrahydropyrimidine and its five- and seven-membered ring analogs were synthesized and their conformational properties investigated by low temperature NMR spectroscopy and DFT theoretical calculations. Restricted rotation of the aryl substituents were observed in all cases and the corresponding barriers determined. In the case of the six-membered ring derivative the additional conformers resulting from a ring inversion process were also detected.