Generation of iPSC line iPSC-FH2.1 in hypoxic conditions from human foreskin fibroblasts

dc.creatorQuesta, María
dc.creatorRomorini, Leonardo
dc.creatorBluguermann, Carolina
dc.creatorSolari, Claudia María
dc.creatorNeiman, Gabriel
dc.creatorLuzzani, Carlos Daniel
dc.creatorScassa, Maria Elida
dc.creatorSevlever, Gustavo
dc.creatorGuberman, Alejandra Sonia
dc.creatorMiriuka, Santiago Gabriel
dc.date.accessioned2018-04-27T19:40:34Z
dc.date.available2018-04-27T19:40:34Z
dc.date.created2018-04-27T19:40:34Z
dc.date.issued2016-01
dc.identifierQuesta, María; Romorini, Leonardo; Bluguermann, Carolina; Solari, Claudia María; Neiman, Gabriel; et al.; Generation of iPSC line iPSC-FH2.1 in hypoxic conditions from human foreskin fibroblasts; Elsevier Science; Stem Cell Research; 16; 2; 1-2016; 300-303
dc.identifier1873-5061
dc.identifierhttp://hdl.handle.net/11336/43745
dc.identifierCONICET Digital
dc.identifierCONICET
dc.description.abstractHuman foreskin fibroblasts were used to generate the iPSC line iPSC-FH2.1 using the EF1a-hSTEMCCA-loxP vector expressing OCT4, SOX2, c-MYC and KLF4, in 5% O2 culture conditions. Stemness was confirmed, as was pluripotency both in vivo and in vitro, in normoxia and hypoxia. Human Embryonic Stem Cell (hESC) line WA-09 and reprogrammed fibroblast primary culture HFF-FM were used as controls.
dc.languageeng
dc.publisherElsevier Science
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.scr.2015.12.026
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1873506115002068
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectInduced Pluripotent Stem Cells
dc.subjectHypoxia
dc.subjectHuman Foreskin Fibroblasts
dc.titleGeneration of iPSC line iPSC-FH2.1 in hypoxic conditions from human foreskin fibroblasts
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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