Modeling cancer immunotherapy: Assessing the effects of lymphocytes on cancer cell growth and motility

dc.creatorRamos, R. A.
dc.creatorZapata, Jair
dc.creatorCondat, Carlos
dc.creatorDeisboeck, Thomas S.
dc.date.accessioned2017-09-28T21:41:16Z
dc.date.accessioned2018-11-06T16:04:00Z
dc.date.available2017-09-28T21:41:16Z
dc.date.available2018-11-06T16:04:00Z
dc.date.created2017-09-28T21:41:16Z
dc.date.issued2013-02
dc.identifierRamos, R. A.; Zapata, Jair; Condat, Carlos; Deisboeck, Thomas S.; Modeling cancer immunotherapy: Assessing the effects of lymphocytes on cancer cell growth and motility; Elsevier Science; Physica A: Statistical Mechanics and its Applications; 392; 10; 2-2013; 2415-2425
dc.identifier0378-4371
dc.identifierhttp://hdl.handle.net/11336/25407
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1904174
dc.description.abstractA mesoscopic model is used to describe the effects of lymphocyte activity on a growing tumor. The model yields novel insights into the tumor–immune system interaction. In particular, we found that the presence of a putative chemotactic messenger that helps guide the lymphocytes towards the tumor is not critical to elicit the anti-tumor effects of the immune system, while lymphocytes that block tumor cell migration contribute to limit cancer expansion and thus have a more significant therapeutic impact.
dc.languageeng
dc.publisherElsevier Science
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.physa.2013.01.047
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S037843711300099X
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectCancer
dc.subjectImmunotherapy
dc.subjectTumor Growth
dc.subjectCell Motility
dc.titleModeling cancer immunotherapy: Assessing the effects of lymphocytes on cancer cell growth and motility
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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