Measuring the composition-curvature coupling in binary lipid membranes by computer simulations

dc.creatorBarragán Vidal, I. A.
dc.creatorRosetti, Carla Mariana
dc.creatorPastorino, Claudio
dc.creatorMüller, M.
dc.date.accessioned2018-01-03T13:55:50Z
dc.date.accessioned2018-11-06T15:28:07Z
dc.date.available2018-01-03T13:55:50Z
dc.date.available2018-11-06T15:28:07Z
dc.date.created2018-01-03T13:55:50Z
dc.date.issued2014-11
dc.identifierMüller, M.; Rosetti, Carla Mariana; Barragán Vidal, I. A.; Pastorino, Claudio; Measuring the composition-curvature coupling in binary lipid membranes by computer simulations; American Institute of Physics; Journal of Chemical Physics; 141; 19; 11-2014; 1-13
dc.identifier0021-9606
dc.identifierhttp://hdl.handle.net/11336/32105
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1897474
dc.description.abstractThe coupling between local composition fluctuations in binary lipid membranes and curvatureaffects the lateral membrane structure. We propose an efficient method to compute the composition-curvature coupling in molecular simulations and apply it to two coarse-grained membrane models—aminimal, implicit-solvent model and the MARTINI model. Both the weak-curvature behavior that istypical for thermal fluctuations of planar bilayer membranes as well as the strong-curvature regimecorresponding to narrow cylindrical membrane tubes are studied by molecular dynamics simulation.The simulation results are analyzed by using a phenomenological model of the thermodynamics ofcurved, mixed bilayer membranes that accounts for the change of the monolayer area upon bending.Additionally the role of thermodynamic characteristics such as the incompatibility between thetwo lipid species and asymmetry of composition are investigated.
dc.languageeng
dc.publisherAmerican Institute of Physics
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1063/1.4901203
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://aip.scitation.org/doi/10.1063/1.4901203
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLipid
dc.subjectMonolayers
dc.subjectFree energy
dc.subjectCritical point phenomena
dc.subjectDoping
dc.titleMeasuring the composition-curvature coupling in binary lipid membranes by computer simulations
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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