Effects of size and surface functionalization of zinc oxide (ZnO) particles on interactions with bovine serum albumin (BSA)

dc.creatorSimonelli, Gabriela
dc.creatorArancibia, Eleuterio Luis
dc.date.accessioned2018-04-24T19:52:57Z
dc.date.accessioned2018-11-06T15:26:36Z
dc.date.available2018-04-24T19:52:57Z
dc.date.available2018-11-06T15:26:36Z
dc.date.created2018-04-24T19:52:57Z
dc.date.issued2015-11
dc.identifierSimonelli, Gabriela; Arancibia, Eleuterio Luis; Effects of size and surface functionalization of zinc oxide (ZnO) particles on interactions with bovine serum albumin (BSA); Elsevier Science; Journal of Molecular Liquids; 211; 11-2015; 742-746
dc.identifier0167-7322
dc.identifierhttp://hdl.handle.net/11336/43331
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1897179
dc.description.abstractIn this work, the behaviour of bovine serum albumin (BSA) interacting with zinc oxide (ZnO) particles functionalized with 3-mercaptopropionic acid (3-MPA) and without any coating has been investigated. Two kinds of ZnO particles of different size and morphology were obtained: microwires (MW) and nanoparticles (NP). The effect of surface modification on the fluorescence properties of ZnO was studied. Typical ZnO green emission due to defects was not observed in the functionalized NP spectrum. Structure alterations of the protein interacting with ZnO particles were evaluated by fluorescence spectroscopy and circular dichroism (CD). Though BSA structure was not significantly perturbed in any case, some conformational changes were observed for BSA interacting with not functionalized MW.
dc.languageeng
dc.publisherElsevier Science
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.molliq.2015.07.075
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0167732215302816
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectZinc oxide
dc.subjectSurface curvature
dc.subject3-Mercaptopropionic acid
dc.subjectCircular dichroism
dc.titleEffects of size and surface functionalization of zinc oxide (ZnO) particles on interactions with bovine serum albumin (BSA)
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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