Cytotoxicity action of an oxidovanadium(IV)-DPPZ complex on MG-63 human osteosarcoma cell line

dc.creatorLeon, Ignacio Esteban
dc.creatorEtcheverry, Susana Beatriz
dc.creatorBaran, Enrique José
dc.date.accessioned2018-06-26T22:28:48Z
dc.date.accessioned2018-11-06T15:10:13Z
dc.date.available2018-06-26T22:28:48Z
dc.date.available2018-11-06T15:10:13Z
dc.date.created2018-06-26T22:28:48Z
dc.date.issued2015-04
dc.identifierLeon, Ignacio Esteban; Etcheverry, Susana Beatriz; Baran, Enrique José; Cytotoxicity action of an oxidovanadium(IV)-DPPZ complex on MG-63 human osteosarcoma cell line; Trade Science Journals; BioTechnology, An Indian Journal; 11; 12; 4-2015; 465-468
dc.identifier0974-7435
dc.identifierhttp://hdl.handle.net/11336/50200
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1894333
dc.description.abstractThe cytotoxicity activity of the recently reported [VO(H2O) 2(SO4)dppz]2H2O complex (dppz = dipyrido[3,2-a:2í,3í- c]phenazine) on MG-63 human osteosarcoma cell line was investigated. It was found that it caused a concentration related inhibitory effect in the concentration range between 5 and 25 µM and diminished the cell viability ca. 40% in the range from 25 to 100 ÏM, without dose/response effects in this range. These biological effects are, in general, similar to those previously reported for the related [VO(ODA)dppz].3H2O (ODA = dianion of oxodiacetic acid) and [VO(ODA)(phen)].1.5H2O (phen = o- phenanthroline) complexes. The importance of the presence of DNAintercalating ligands in these complexes is emphasized.
dc.languageeng
dc.publisherTrade Science Journals
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.tsijournals.com/abstract/cytotoxicity-action-of-an-oxidovanadiumivdppz-complex-on-mg63-human-osteosarcoma-cell-line-2208.html
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectOxidovanadium(IV)
dc.subjectDPPZ
dc.subjectMetallointercalators
dc.subjectHuman osteosarcoma cell line
dc.titleCytotoxicity action of an oxidovanadium(IV)-DPPZ complex on MG-63 human osteosarcoma cell line
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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