dc.creator | Díaz, Jimena Estela | |
dc.creator | Ranieri, Silvia | |
dc.creator | Gruber, Nadia | |
dc.creator | Orelli, Liliana Raquel | |
dc.date.accessioned | 2018-06-18T19:16:40Z | |
dc.date.accessioned | 2018-11-06T14:52:38Z | |
dc.date.available | 2018-06-18T19:16:40Z | |
dc.date.available | 2018-11-06T14:52:38Z | |
dc.date.created | 2018-06-18T19:16:40Z | |
dc.date.issued | 2017-06 | |
dc.identifier | Díaz, Jimena Estela; Ranieri, Silvia; Gruber, Nadia; Orelli, Liliana Raquel; Syntheses of 3,4- and 1,4-dihydroquinazolines from 2-aminobenzylamine; Beilstein-Institut; Beilstein Journal Of Organic Chemistry; 13; 6-2017; 1470-1477 | |
dc.identifier | 1860-5397 | |
dc.identifier | http://hdl.handle.net/11336/49091 | |
dc.identifier | CONICET Digital | |
dc.identifier | CONICET | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1891261 | |
dc.description.abstract | A straightforward strategy for the synthesis of dihydroquinazolines is presented, which allows for the preparation of 3,4- and 1,4-dihydroquinazolines with different substitution patterns from 2-aminobenzylamine (2-ABA) as common precursor. The required functionalization of both amino groups present in 2-ABA was achieved by different routes involving selective N-acylation and cesium carbonate mediated N-alkylation reactions, avoiding protection/deprotection steps. The heterocycles were efficiently synthesized in short reaction times by microwave-assisted ring closure of the corresponding aminoamides promoted by ethyl polyphosphate (PPE). | |
dc.language | eng | |
dc.publisher | Beilstein-Institut | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550820/ | |
dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3762/bjoc.13.145 | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.beilstein-journals.org/bjoc/articles/13/145 | |
dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | Dihydroquinazolines | |
dc.subject | N-alkylations | |
dc.subject | N-acylations | |
dc.subject | Microwaves | |
dc.subject | PPE | |
dc.title | Syntheses of 3,4- and 1,4-dihydroquinazolines from 2-aminobenzylamine | |
dc.type | Artículos de revistas | |
dc.type | Artículos de revistas | |
dc.type | Artículos de revistas | |