Expedient synthesis of 1,6-anhydro-α-D-galactofuranose, a useful intermediate for glycobiological tools

dc.creatorBaldoni, Luciana
dc.creatorMarino, María Carla
dc.date.accessioned2016-11-11T19:03:22Z
dc.date.accessioned2018-11-06T14:50:02Z
dc.date.available2016-11-11T19:03:22Z
dc.date.available2018-11-06T14:50:02Z
dc.date.created2016-11-11T19:03:22Z
dc.date.issued2014-07
dc.identifierBaldoni, Luciana; Marino, María Carla; Expedient synthesis of 1,6-anhydro-α-D-galactofuranose, a useful intermediate for glycobiological tools; Beilstein-institut; Beilstein Journal Of Organic Chemistry; 10; 7-2014; 1651-1656
dc.identifier1860-5397
dc.identifierhttp://hdl.handle.net/11336/8159
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1890891
dc.description.abstractA new and efficient three-step procedure for the synthesis of 1,6-anhydro-α-D-galactofuranose is described. The key step involves the formation of the galactofuranosyl iodide by treatment of per-O-TBS-D-Galf with TMSI, the selective 6-O-desilylation by an excess of TMSI, and the simultaneous nucleophilic attack of the 6-hydroxy group on the anomeric carbon, with the iodide as a good leaving group. This compound is a good precursor for building blocks for the construction of 1→6 linkages.
dc.languageeng
dc.publisherBeilstein-institut
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.beilstein-journals.org/bjoc/single/articleFullText.htm?publicId=1860-5397-10-172
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.3762/bjoc.10.172
dc.relationinfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143087/
dc.rightshttps://creativecommons.org/licenses/by/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGALACTOFURANOSE
dc.subjectGLYCOSYL IODIDES
dc.subjectSYNTHETIC INTERMEDIATES
dc.titleExpedient synthesis of 1,6-anhydro-α-D-galactofuranose, a useful intermediate for glycobiological tools
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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