Anti-human proacrosin antibody inhibits the zona pellucida (ZP)-induced acrosome reaction of ZP-bound spermatozoa

dc.creatorVeaute, Carolina Melania Isabel
dc.creatorLiu, D. Y.
dc.creatorFurlong, L. I.
dc.creatorBiancotti, J. C.
dc.creatorBaker, H.
dc.creatorVazquez, Monica Hebe
dc.date.accessioned2017-03-27T15:49:53Z
dc.date.accessioned2018-11-06T14:44:29Z
dc.date.available2017-03-27T15:49:53Z
dc.date.available2018-11-06T14:44:29Z
dc.date.created2017-03-27T15:49:53Z
dc.date.issued2010-05-01
dc.identifierVeaute, Carolina Melania Isabel; Liu, D. Y.; Furlong, L. I.; Biancotti, J. C.; Baker, H. ; et al.; Anti-human proacrosin antibody inhibits the zona pellucida (ZP)-induced acrosome reaction of ZP-bound spermatozoa; Elsevier Inc; Fertility And Sterility; 93; 7; 1-5-2010; 2456-2459
dc.identifier0015-0282
dc.identifierhttp://hdl.handle.net/11336/14258
dc.identifier1556-5653
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1889724
dc.description.abstractThe anti-acrosin monoclonal antibody AcrC5F10 inhibited proacrosin activation, proacrosin-human zona pellucida glycoprotein A (ZPA) binding, and the zona pellucida (ZP)-induced acrosome reaction of the ZP-bound spermatozoa but had no significant effect on sperm-ZP binding. These results suggest that proacrosin-acrosin may play an important role in the ZP-induced acrosome reaction of spermatozoa after primary binding to the ZP.
dc.languageeng
dc.publisherElsevier Inc
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.fertstert.org/article/S0015-0282(09)03518-3/abstract
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.fertnstert.2009.08.040
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectHUMAN
dc.subjectFERTILIZATION
dc.subjectSPERMATOZOA
dc.subjectOOCYTE
dc.subjectPROACROSIN
dc.subjectACROSIN
dc.subjectANTIBODIES
dc.subjectACROSOME REACTION
dc.titleAnti-human proacrosin antibody inhibits the zona pellucida (ZP)-induced acrosome reaction of ZP-bound spermatozoa
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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