Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls

dc.creatorFernandez, María Elena
dc.creatorGoszczynski, Daniel Estanislao
dc.creatorPrando, Alberto José
dc.creatorPeral Garcia, Pilar
dc.creatorBaldo, Andrés
dc.creatorGiovambattista, Guillermo
dc.creatorLiron, Juan Pedro
dc.date.accessioned2017-01-24T15:34:15Z
dc.date.accessioned2018-11-06T14:20:45Z
dc.date.available2017-01-24T15:34:15Z
dc.date.available2018-11-06T14:20:45Z
dc.date.created2017-01-24T15:34:15Z
dc.date.issued2014-09
dc.identifierFernandez, María Elena; Goszczynski, Daniel Estanislao; Prando, Alberto José; Peral Garcia, Pilar; Baldo, Andrés; et al.; Assessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls; BioMed Central; Journal of Animal Science and Technology; 56; 9-2014; 17-20
dc.identifier2055-0391
dc.identifierhttp://hdl.handle.net/11336/11791
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1885420
dc.description.abstractPuberty is a stage of sexual development determined by the interaction of many loci and environmental factors. Identification of genes contributing to genetic variation in this character can assist with selection for early pubertal bulls, improving genetic progress in livestock breeding. Thyroid hormones play an important role in sexual development and spermatogenic function. The objective of this study was to evaluate the association between single nucleotide polymorphisms (SNPs) located in thyroglobulin(TG) gene with age of puberty in Angus bulls. Four SNPs were genotyped in 273 animals using SEQUENOM technology and the association between markers and puberty age was analyzed. Results showed a significant association (P < 0.05) between these markers and puberty age estimated at a sperm concentration of 50 million and a progressive motility of 10%. This is the first report of an association of TG polymorphisms with age of puberty in bulls, and results suggest the importance of thyroidal regulation in bovine sexual development and arrival to puberty.
dc.languageeng
dc.publisherBioMed Central
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1186/2055-0391-56-17
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://janimscitechnol.biomedcentral.com/articles/10.1186/2055-0391-56-17
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBovine
dc.subjectPuberty
dc.subjectPolymorphism
dc.subjectThyroglobulin
dc.subjectAssociation study
dc.titleAssessing the association of single nucleotide polymorphisms in thyroglobulin gene with age of puberty in bulls
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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