A Solvent-free Method for Synthesis of Dihydroangelicins using Microwaves

dc.creatorRuiz, Diego Manuel
dc.creatorAutino, Juan Carlos
dc.creatorRomanelli, Gustavo Pablo
dc.date.accessioned2018-04-16T21:42:43Z
dc.date.accessioned2018-11-06T14:20:35Z
dc.date.available2018-04-16T21:42:43Z
dc.date.available2018-11-06T14:20:35Z
dc.date.created2018-04-16T21:42:43Z
dc.date.issued2017-04
dc.identifierRuiz, Diego Manuel; Autino, Juan Carlos; Romanelli, Gustavo Pablo; A Solvent-free Method for Synthesis of Dihydroangelicins using Microwaves; Bentham Science Publishers; Current Green Chemistry; 3; 3; 4-2017; 242-247
dc.identifier2213-3461
dc.identifierhttp://hdl.handle.net/11336/42230
dc.identifierCONICET Digital
dc.identifierCONICET
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1885396
dc.description.abstractBackground: Dihydrofurocoumarins are a large family of compounds, among them, dihydroangelicins and dihydropsoralens, are present in various plant species with varied biological activity. Several strategies have been developed for synthesizing these compounds and various catalysts have been used for this purpose. Methods: In this work, we report the synthesis of 8,9-dihydrofuran [2, 3-h] coumarins using allyloxycoumarin cycloaddition in sustainable conditions: absence of solvents, application of microwave radiation, and insoluble acid catalysis by means of heteropolyacids with Preyssler structure, [H14(NaP5MoW29O110)]. Conclusion: With these conditions, and testing sustainability by means of Eco-Scale and E-factor, we replace the use of solvents and mineral acids having a great impact on the environment with a solid, easily recoverable heteropolyacid.
dc.languageeng
dc.publisherBentham Science Publishers
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.2174/2213346104666170224101037
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/150409/article
dc.rightshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectDihydroangelicins
dc.subjectDihydrofuocoumarins
dc.subjectMicrowave radiation
dc.subjectGreen Chemistry
dc.subjectheteropolyacid
dc.subjectPreyssler structure
dc.titleA Solvent-free Method for Synthesis of Dihydroangelicins using Microwaves
dc.typeArtículos de revistas
dc.typeArtículos de revistas
dc.typeArtículos de revistas


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