Argentina
| info:eu-repo/semantics/article
Galectin-1 suppresses experimental colitis in mice
| dc.creator | Santucci, Luca | |
| dc.creator | Fiorucci, Stefano | |
| dc.creator | Rubinstein, Natalia | |
| dc.creator | Mencarelli, Andrea | |
| dc.creator | Pallazzeti, Barbara | |
| dc.creator | Federici, Barbara | |
| dc.creator | Rabinovich, Gabriel Adrián | |
| dc.creator | Morelli, Antonio | |
| dc.date.accessioned | 2018-02-11T22:32:51Z | |
| dc.date.available | 2018-02-11T22:32:51Z | |
| dc.date.created | 2018-02-11T22:32:51Z | |
| dc.date.issued | 2003-05 | |
| dc.identifier | Santucci, Luca; Fiorucci, Stefano; Rubinstein, Natalia; Mencarelli, Andrea; Pallazzeti, Barbara; et al.; Galectin-1 suppresses experimental colitis in mice; American Gastroenterological Association; Gastroenterology; 124; 5; 5-2003; 1381-1394 | |
| dc.identifier | 0016-5085 | |
| dc.identifier | http://hdl.handle.net/11336/36410 | |
| dc.identifier | CONICET Digital | |
| dc.identifier | CONICET | |
| dc.description.abstract | Uncontrolled T-cell activation plays a critical role in the pathogenesis of inflammatory bowel diseases. Therefore, pharmacologic strategies directed to restore the normal responsiveness of the immune system by deleting inappropriately activated T cells could be efficacious in the treatment of these pathologic conditions. Galectin-1 is an endogenous lectin expressed in lymphoid organs that plays a role in the maintenance of central and peripheral tolerance. The aim of the present study was to evaluate the therapeutic effects of galectin-1 on T-helper cell type 1-mediated experimental colitis induced by intrarectal administration of 2,4,6-trinitrobenzene sulfonic acid (TNBS) in mice. | |
| dc.language | eng | |
| dc.publisher | American Gastroenterological Association | |
| dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0016508503002671 | |
| dc.relation | info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/S0016-5085(03)00267-1 | |
| dc.relation | info:eu-repo/semantics/altIdentifier/pmid/12730878 | |
| dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.subject | Autoimmune Colitis | |
| dc.subject | Galectin-1 | |
| dc.subject | Tumor Necrosis Factor Alpha | |
| dc.subject | Human Recombinant Galectin | |
| dc.subject | Irritable Bowel Disease | |
| dc.title | Galectin-1 suppresses experimental colitis in mice | |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:ar-repo/semantics/artículo | |
| dc.type | info:eu-repo/semantics/publishedVersion |