dc.creator | Palazzolo, Martín Alejandro | |
dc.creator | Nigro, Mariano José | |
dc.creator | Iribarren, Adolfo Marcelo | |
dc.creator | Lewkowicz, Elizabeth Sandra | |
dc.date.accessioned | 2018-04-17T21:43:23Z | |
dc.date.accessioned | 2018-11-06T14:15:15Z | |
dc.date.available | 2018-04-17T21:43:23Z | |
dc.date.available | 2018-11-06T14:15:15Z | |
dc.date.created | 2018-04-17T21:43:23Z | |
dc.date.issued | 2016-02 | |
dc.identifier | Palazzolo, Martín Alejandro; Nigro, Mariano José; Iribarren, Adolfo Marcelo; Lewkowicz, Elizabeth Sandra; A Chemoenzymatic Route To Prepare Acyclic Nucleoside Analogues; Wiley VCH Verlag; European Journal of Organic Chemistry; 2016; 5; 2-2016; 921-924 | |
dc.identifier | 1434-193X | |
dc.identifier | http://hdl.handle.net/11336/42399 | |
dc.identifier | CONICET Digital | |
dc.identifier | CONICET | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1884426 | |
dc.description.abstract | Acyclic nucleosides are potential antiviral and antitumor agents. In this work, their preparation through a novel chemoenzymatic procedure involving theN-alkylation of a nucleobase and subsequent aldol condensation catalyzed by a dihydroxyacetone phosphate-dependant aldolase (Rabbit Muscle Aldolase, RAMA) is described. | |
dc.language | eng | |
dc.publisher | Wiley VCH Verlag | |
dc.relation | info:eu-repo/semantics/altIdentifier/doi/https://doi.org/10.1002/ejoc.201501412 | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.201501412 | |
dc.rights | https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.subject | ACYCLIC NUCLEOSIDES | |
dc.subject | BIOCATALYSIS | |
dc.title | A Chemoenzymatic Route To Prepare Acyclic Nucleoside Analogues | |
dc.type | Artículos de revistas | |
dc.type | Artículos de revistas | |
dc.type | Artículos de revistas | |