dc.creator | Dalghi, Marianela Gisela | |
dc.creator | Ferreira Gomes, Mariela Soledad | |
dc.creator | Rossi, Juan Pablo Francisco | |
dc.date.accessioned | 2018-06-04T19:57:29Z | |
dc.date.accessioned | 2018-11-06T14:11:42Z | |
dc.date.available | 2018-06-04T19:57:29Z | |
dc.date.available | 2018-11-06T14:11:42Z | |
dc.date.created | 2018-06-04T19:57:29Z | |
dc.date.issued | 2017-11 | |
dc.identifier | Dalghi, Marianela Gisela; Ferreira Gomes, Mariela Soledad; Rossi, Juan Pablo Francisco; Regulation of the Plasma Membrane Calcium ATPases by the actin cytoskeleton; Academic Press Inc Elsevier Science; Biochemical and Biophysical Research Communications; 11-2017; 1-12 | |
dc.identifier | 0006-291X | |
dc.identifier | http://hdl.handle.net/11336/47201 | |
dc.identifier | CONICET Digital | |
dc.identifier | CONICET | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1883729 | |
dc.description.abstract | Associations between the cortical cytoskeleton and the components of the plasma membrane are no longer considered to be merely of structural and mechanical nature but are nowadays recognized as dynamic interactions that modulate a plethora of cellular responses. Reorganization of actin filaments upon diverse stimuli - among which is the rise in cytosolic Ca2+ – is involved in cell motility and adhesion, phagocytosis, cytokinesis, and secretion. Actin dynamics also participates in the regulation of ion transport across the membranes where it not only plays a key role in the delivery and stabilization of channels and transporters in the plasma membrane but also in the regulation of their activity. The recently described functional interaction between actin and the Plasma Membrane Ca2+-ATPase (PMCA) represents a novel regulatory mechanism of the pump at the time that unveils a new pathway by which the cortical actin cytoskeleton participates in the regulation of cytosolic Ca2+ homeostasis. In this review, we summarize the current knowledge on the interaction between the cortical actin cytoskeleton and the PMCA and discuss the possible mechanisms that may explain the pump's modulation. | |
dc.language | eng | |
dc.publisher | Academic Press Inc Elsevier Science | |
dc.relation | info:eu-repo/semantics/altIdentifier/doi/https://dx.doi.org/10.1016/j.bbrc.2017.11.151 | |
dc.relation | info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0006291X17323288 | |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.5/ar/ | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.subject | ACTIN | |
dc.subject | CALCIUM | |
dc.subject | CORTICAL CYTOSKELETON | |
dc.subject | MODULATION | |
dc.subject | PMCA | |
dc.title | Regulation of the Plasma Membrane Calcium ATPases by the actin cytoskeleton | |
dc.type | Artículos de revistas | |
dc.type | Artículos de revistas | |
dc.type | Artículos de revistas | |