Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells

dc.creatorFernández, Marisa Mariel
dc.creatorFerragut, Fátima
dc.creatorCardenas Delgado, Victor Manuel
dc.creatorBracalente, María Candelaria
dc.creatorBravo, Alicia Ines
dc.creatorCagnoni, Alejandro
dc.creatorNuñez, Myriam Carmen
dc.creatorMorosi, Luciano Gastón
dc.creatorQuintá, Héctor Ramiro
dc.creatorEspelt, Maria Victoria
dc.creatorTroncoso, María Fernanda
dc.creatorWolfenstein, Carlota Elisa
dc.creatorMariño, Karina Valeria
dc.creatorMalchiodi, Emilio Luis
dc.creatorRabinovich, Gabriel Adrián
dc.creatorElola, Maria Teresa
dc.date.accessioned2017-09-01T18:43:28Z
dc.date.available2017-09-01T18:43:28Z
dc.date.created2017-09-01T18:43:28Z
dc.date.issued2016-04-26
dc.identifierFernández, Marisa Mariel; Ferragut, Fátima; Cardenas Delgado, Victor Manuel; Bracalente, María Candelaria; Bravo, Alicia Ines; et al.; Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells; Elsevier Science; Biochimica et Biophysica Acta- General Subjects; 1860; 10; 26-4-2016; 2255-2268
dc.identifier0304-4165
dc.identifierhttp://hdl.handle.net/11336/23462
dc.identifier1878-2434
dc.identifierCONICET Digital
dc.identifierCONICET
dc.description.abstractWe previously demonstrated that the activated leukocyte cell adhesion molecule (ALCAM/CD166) can interact with galectin-8 (Gal-8) in endothelial cells. ALCAM is a member of the immunoglobulin superfamily that promotes homophilic and heterophilic cell-cell interactions. Gal-8 is a "tandem-repeat"-type galectin, known as a matricellular protein involved in cell adhesion. Here, we analyzed the physical interaction between both molecules in breast cancer cells and the functional relevance of this phenomenon.
dc.languageeng
dc.publisherElsevier Science
dc.relationinfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0304416516301246
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.bbagen.2016.04.019.
dc.relationinfo:eu-repo/semantics/altIdentifier/url/27130882
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectGalectin-8
dc.subjectBreast Cancer Cell
dc.subjectAlcam/Cd166
dc.subjectReceptor Segregation
dc.titleGlycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo
dc.typeinfo:eu-repo/semantics/publishedVersion


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